Evidence map›Paper›PMID 37193745›Full record

ArticleScientific reports2023

Quaternization of high molecular weight chitosan for increasing intestinal drug absorption using Caco-2 cells as an in vitro intestinal model.

Ratjika Wongwanakul, Sasitorn Aueviriyavit, Tomomi Furihata, Pattarapond Gonil, Warayuth Sajomsang, Rawiwan Maniratanachote, Suree Jianmongkol

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ratjika WongwanakulDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, 254 Phayathai Road, Bangkok, 10330, Thailand.
Sasitorn AueviriyavitNational Nanotechnology Center, National Science and Technology Development Agency, 111 Thailand Science Park, Pathum Thani, 12120, Thailand. sasitorn@nanotec.or.th.
Tomomi FurihataLaboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Pattarapond GonilNational Nanotechnology Center, National Science and Technology Development Agency, 111 Thailand Science Park, Pathum Thani, 12120, Thailand.
Warayuth SajomsangNational Nanotechnology Center, National Science and Technology Development Agency, 111 Thailand Science Park, Pathum Thani, 12120, Thailand.
Rawiwan ManiratanachoteToxicology and Bio Evaluation Service Center, National Science and Technology Development Agency, Pathum Thani, Thailand.
Suree JianmongkolDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, 254 Phayathai Road, Bangkok, 10330, Thailand. suree.j@pharm.chula.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Potential use of a quaternized chitosan (MW 600 kDa) with 65% of 3-chloro-2-hydroxypropyltrimethylammonium (600-HPTChC

Indexed as

ChitosanCaco-2 CellsHumansIntestinal AbsorptionIntestinal MucosaMolecular WeightOccludinTight JunctionsChitosanOccludin

Identifiers

PMID37193745
PMCPMC10188607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.