ArticleArthroplasty today2023
Patient-Reported Outcomes of Kinematic vs Mechanical Alignment in Total Knee Arthroplasty: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Article in Arthroplasty today, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Kinematic Alignment Does Not Result in Clinically Important Improvements After TKA Compared With Mechanical Alignment: A Meta-analysis of Randomized Trials.Clinical orthopaedics and related research · 2025Pooled it
- Six-degree-of-freedom knee motion during treadmill walking in mechanically and kinematically aligned TKA.Scientific reports · 2026Trial
- Association between Coronal Mechanical Axis Correction and Early Functional Outcomes after Primary Total Knee Arthroplasty: A Retrospective Observational Study.Journal of orthopaedic case reports · 2026Article
- Patellofemoral outcomes after kinematic versus mechanical alignment in primary total knee arthroplasty : a focused scoping review of head-to-head comparative studies.Bone & joint open · 2026Article
- Biomechanical analysis of surgical alignment and design in total knee arthroplasty.Archives of orthopaedic and trauma surgery · 2026Article
- Alignment Philosophies in Total Knee Arthroplasty: A Comprehensive Narrative Review.Arthroplasty today · 2026Article
- Article
- Mechanical Versus Restrictive Kinematic Alignment in Robotic-Assisted Total Knee Arthroplasty: A Randomized Controlled Trial.Diagnostics (Basel, Switzerland) · 2025Article
- Changes in coronal plane alignment of the knee classification do not significantly influence outcomes after restricted kinematic alignment total knee arthroplasty.Journal of experimental orthopaedics · 2025Article
- Increased varus deformity requires greater personalisation of alignment: A finite element biomechanical study.Journal of experimental orthopaedics · 2025Article
- Inverse Kinematic Alignment in Robot-Assisted Total Knee Arthroplasty: A Simplified Surgical Technique.Arthroplasty today · 2025Article
- Prospective Comparison of Short-Term Outcomes in Kinematic and Mechanical Alignment Total Knee Arthroplasty.Clinics and practice · 2025Article
- Lateral Instability 13 Years After Kinematically Aligned Total Knee Arthroplasty.Arthroplasty today · 2025Article
- Kinematic versus mechanical alignment: A systematic review of systematic reviews and meta-analyses of randomised controlled trials.Journal of experimental orthopaedics · 2024Review
- The epidemic of alignment classifications in total knee arthroplasty forgives the kinematic of the human knee.Journal of experimental orthopaedics · 2024Article
- No difference in postoperative patient satisfaction rates between mechanical and kinematic alignment total knee arthroplasty: A systematic review.Journal of experimental orthopaedics · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Total knee arthroplasty (TKA) is an effective treatment method for severe osteoarthritis of the knee. Poor alignment of a knee replacement has been associated with suboptimal clinical results. Traditionally, mechanical alignment (MA) has been considered the gold standard. In light of reports of decreased satisfaction with TKA, a new technique called kinematic alignment (KA) has been developed. The purpose of this study is to (1) review the results of KA and MA for TKA in randomized controlled trials based on the Western Ontario and McMaster Universities Arthritis Index score, the Oxford Knee Score, and the Knee Society Scores, (2) perform a meta-analyses of the randomized controlled trials with baseline and follow-up values of these parameters, and (3) discuss other shortcomings of this literature from the perspective of study design and execution. Methods: Two independent reviewers performed a systematic review of the English literature using the Embase, Scopus, and PubMed databases searching for randomized controlled trials of MA vs KA in TKA. Of the initial 481 published reports, 6 studies were included in the final review for meta-analysis. The individual studies were then analyzed to evaluate for risks of bias and inconsistencies of methodology. Results: A majority of studies demonstrated low risk of bias. All studies had fundamental technical issues by utilizing different techniques to achieve KA vs MA. There was no significant difference between KA and MA in these studies. Conclusions: There is no significant difference in any outcomes measured between KA and MA in TKA. Both statistical and methodological factors diminish the value of these conclusions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.