A Case of Non-cirrhotic Hyperammonemic Encephalopathy in a Patient With Metastatic Gastrointestinal Stromal Tumor.

Il Seok D Jeong, Parinaz Abiri, Johnny Cai, Catherine Yim, Leland Powell

Open access · diamondAbstract readCase Reports

In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 91% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Il Seok D JeongInternal Medicine, Olive View - University of California, Los Angeles (UCLA) Medical Center, Sylmar, USA.

Parinaz AbiriInternal Medicine, Olive View - University of California, Los Angeles (UCLA) Medical Center, Sylmar, USA.

Johnny CaiHematology and Oncology, Olive View - University of California, Los Angeles (UCLA) Medical Center, Sylmar, USA.

Catherine YimNeurology/Radiology, Olive View - University of California, Los Angeles (UCLA) Medical Center, Sylmar, USA.

Leland PowellHematology and Oncology, Olive View - University of California, Los Angeles (UCLA) Medical Center, Sylmar, USA.

Olive View-UCLA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute toxic encephalopathy (ATE) is a widely recognized medical emergency with an expansive differential. One particular known etiology for ATE is elevated ammonia, a powerful neurotoxin that often presents with clinical findings of confusion, disorientation, tremors, and in severe cases, coma and death. Hyperammonemia is most commonly associated with liver disease and presents as hepatic encephalopathy in the setting of decompensated cirrhosis; however, in rare cases, a patient may suffer from non-cirrhotic hyperammonemic encephalopathy. We describe the case of a 61-year-old male with metastatic gastrointestinal stromal tumor who was diagnosed with non-cirrhotic hyperammonemic encephalopathy, and briefly explore the literature describing its mechanisms.

Indexed as

gastrointestinal stromal tumor (gist)hyperammonemiahyperammonemia-encephalopathynon-cirrhotic hyperammonemiasunitinibtyrosine kinase inhibitors (tki)

Identifiers

PMID37193452

DOI10.7759/cureus.37541

PMCPMC10182871

OpenAlexW4365458249

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.