Evidence map›Paper›PMID 37193446›Full record

ArticleCureus2023

To Bleed or Not to Bleed.

Peter A Iskander, Syed Muhammad Hussain Zaidi, Jiayi Zheng, Anthony Iskander, Mark M Aloysius, Vikas Khurana, Simin Nasr

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Peter A IskanderInternal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA.
Syed Muhammad Hussain ZaidiInternal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA.
Jiayi ZhengInternal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA.
Anthony IskanderInternal Medicine, Xavier University School of Medicine, Oranjestad, ABW.
Mark M AloysiusInternal Medicine, The Wright Center for Graduate Medical Education, Scranton, USA.
Vikas KhuranaGastroenterology, The Wright Center for Graduate Medical Education, Scranton, USA.
Simin NasrFamily Medicine, The Wright Center for Graduate Medical Education, Scranton, USA.
The Wright Center for Graduate Medical Education · USAvalon University School of Medicine · CW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The location of gastrointestinal (GI) bleeding can be characterized based on the characteristics of the bowel movements these patients present with. Bright red blood per rectum is usually associated with a lower bleed; if brisk and significant enough, however, upper bleeds can present similarly. Melenic or "tar-colored" bowel movements are more likely to occur from upper bleeds as the color is secondary to digestion of hemoglobin as it passes through the GI tract. At times, there can be a mix of the two which can make a clinical decision for intervention less obvious. To make matters more difficult, some of these patients can be on anticoagulation therapy for a myriad of reasons. Risks versus benefits at these times need to be weighed as holding this therapy may make the patients more prone to clotting while continuation would increase likelihood of bleeding. We present a case of a hypercoagulable patient who was started on rivaroxaban for history of pulmonary embolism; this led to the onset of an acute GI bleed from a duodenal diverticulum requiring endoscopic intervention. Although this can be a known effect of the therapy, the severity of bleed and changes in hemodynamics can warrant very different management strategies.

Indexed as

anticoagulationdirect oral anticoagulant (doac)doacendoscopygastrointestinal bleed

Identifiers

PMID37193446
PMCPMC10183236
OpenAlexW4365504342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.