ArticleAmerican journal of translational research2023
The relationship between peripheral blood soluble ST2, BNP levels, cardiac function, and prognosis in patients with heart failure.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Metoprolol-spironolactone combination for coronary heart disease with concurrent heart failure: impact on cardiac function.American journal of translational research · 2026Article
- Combining clinical markers can predict mortality in NYHA IV heart failure.Scientific reports · 2025Article
- Preventive and Therapeutic Effects of Crocetin in Rats with Heart Failure.Pharmaceuticals (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze the relationship between peripheral blood soluble growth-stimulated expression gene 2 protein (sST2) and B-type natriuretic peptide (BNP) levels and cardiac function and prognosis in patients with heart failure (HF).
methodsHF patients (n = 183) and 50 healthy volunteers were enrolled in this retrospective study. The relationships between peripheral blood sST2 and BNP levels and cardiac function in patients with HF were analyzed by Pearson's correlation analysis. HF patients were divided into a poor prognosis group (n = 25) and a good prognosis group (n = 158) during the 1-year follow-up period, and variables that might affect the prognosis of HF patients were screened by univariate analysis.
resultThe peripheral blood sST2 and BNP levels of HF patients were higher than those of healthy controls. Compared to the good prognosis group, the poor prognosis group had higher LVDs, LVDd, but lower LVEF, D-dimer, hemoglobin (HB) levels, uric acid, sST2, BNP, troponin I (TnI), creatine kinase isozyme-MB, myoglobin, creatinine (Cr), and hypersensitive C-reactive protein. LVEF, sST2, BNP, TnI, and HB were independent risk factors affecting the prognosis of patients with HF. Higher levels of peripheral blood sST2 and BNP were associated with the worse prognosis in HF.
conclusionPeripheral blood sST2 and BNP levels in HF patients were correlated with cardiac function. LVEF, sST2, BNP, TnI, and HB were independent risk factors affecting the prognosis of HF patients, among which sST2 and BNP were all negatively correlated with prognosis.
Indexed as
Identifiers
37193147PMC10182529W4376870948What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.