Evidence map›Paper›PMID 37192814›Full record

ArticleRNA (New York, N.Y.)2023

Nanopore-based RNA sequencing deciphers the formation, processing, and modification steps of rRNA intermediates in archaea.

Felix Grünberger, Michael Jüttner, Robert Knüppel, Sébastien Ferreira-Cerca, Dina Grohmann

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  7. Review
  8. Journal of bacteriology · 2025
    Review
  9. Article
  10. Small nucleolar RNAs: the hidden precursors of cancer ribosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  11. Circular RNAs in Archaea.Advances in experimental medicine and biology · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Felix GrünbergerInstitute of Biochemistry, Genetics and Microbiology, Institute of Microbiology and Archaea Centre, Single-Molecule Biochemistry Lab and Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Bavaria 93053, Germany.ORCID 0000-0001-7444-2408
Michael JüttnerRegensburg Center for Biochemistry, Biochemistry III-Institute for Biochemistry, Genetics and Microbiology, University of Regensburg, Regensburg, Bavaria 93053, Germany.
Robert KnüppelRegensburg Center for Biochemistry, Biochemistry III-Institute for Biochemistry, Genetics and Microbiology, University of Regensburg, Regensburg, Bavaria 93053, Germany.
Sébastien Ferreira-CercaRegensburg Center for Biochemistry, Biochemistry III-Institute for Biochemistry, Genetics and Microbiology, University of Regensburg, Regensburg, Bavaria 93053, Germany sebastien.ferreira-cerca@polytechnique.edu dina.grohmann@ur.de.ORCID 0000-0002-0522-843X
Dina GrohmannInstitute of Biochemistry, Genetics and Microbiology, Institute of Microbiology and Archaea Centre, Single-Molecule Biochemistry Lab and Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Bavaria 93053, Germany sebastien.ferreira-cerca@polytechnique.edu dina.grohmann@ur.de.ORCID 0000-0002-0570-2517
University of Regensburg · DECentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ribosomal RNA (rRNA) maturation in archaea is a complex multistep process that requires well-defined endo- and exoribonuclease activities to generate fully mature linear rRNAs. However, technical challenges prevented detailed mapping of rRNA processing steps and a systematic analysis of rRNA maturation pathways across the tree of life. In this study, we used long-read (PCR)-cDNA and direct RNA nanopore-based sequencing to study rRNA maturation in three archaeal model organisms, namely the Euryarchaea

Indexed as

NanoporesNanopore SequencingArchaeaDNA, ComplementaryRNARNA, RibosomalSequence Analysis, RNADNA, ComplementaryRNARNA, RibosomalNanopore sequencingribosomal RNARNA modificationsRNA processing; archaea

Identifiers

PMID37192814
PMCPMC10351888
OpenAlexW4376648460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.