ArticleJournal of affective disorders2023
Patterns of demoralization and anhedonia during early substance use disorder treatment and associations with treatment attrition.
Article in Journal of affective disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Demoralization, employment status, and early symptom reduction as correlates of treatment discontinuation in outpatient alcohol use disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026Article
- Interformat equivalence between paper and electronic administrations of the self-assessment anhedonia scale in a substance use disorder clinical sample.Frontiers in psychology · 2026Article
- Tracking the longitudinal course of physiologic and mental health functioning among individuals in substance use disorder treatment.Frontiers in psychiatry · 2026Article
- Beyond Motor Decline in ALS: Patient-Centered Insights into Non-Motor Manifestations.Medicina (Kaunas, Lithuania) · 2025Article
- Perceived stigma and its role in substance use disorder treatment completion.The American journal of drug and alcohol abuse · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundAlthough depressive symptoms represent a promising therapeutic target to promote recovery from substance use disorders (SUD), heterogeneity in their diagnostic presentation often hinders the ability to effectively tailor treatment. We sought to identify subgroups of individuals varying in depressive symptom phenotypes (i.e., demoralization, anhedonia), and examined whether these subgroups were associated with patient demographics, psychosocial health, and treatment attrition.
methodsPatients (N = 10,103, 69.2 % male) were drawn from a dataset of individuals who presented for admission to SUD treatment in the US. Participants reported on their demoralization and anhedonia approximately weekly for the first month of treatment, and on their demographics, psychosocial health, and primary substance at intake. Longitudinal latent profile analysis examined patterns of demoralization and anhedonia with treatment attrition as a distal outcome.
resultsFour subgroups of individuals emerged: (1) High demoralization and anhedonia, (2) Remitting demoralization and anhedonia, (3) High demoralization, low anhedonia, and (4) Low demoralization and anhedonia. Relative to the Low demoralization and anhedonia subgroup, all the other profiles were more likely to discontinue treatment. Numerous between-profile differences were observed with regard to demographics, psychosocial health, and primary substance. LIMITATIONS: The racial and ethnic background of the sample was skewed towards White individuals; future research is needed to determine the generalizability of our findings to minoritized racial and ethnic groups.
conclusionsWe identified four clinical profiles that varied in the joint course of demoralization and anhedonia. Findings suggest specific subgroups might benefit from additional interventions and treatments that address their unique mental health needs during SUD recovery.
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