ArticlePediatric surgery international2023
Correlation of ectopic distal location of papilla of Vater and clinical characteristics in pediatric choledochal cysts.
Article in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Pathological analysis of liver and cyst wall in prenatally diagnosed choledochal cysts in children.European journal of pediatrics · 2026Article
- Comparison of the current characteristics and management of congenital biliary dilatation with and without a fetal diagnosis: report of 231 consecutive cases from the Kyushu Pediatric Surgery Study Group in Japan over the past decade.Pediatric surgery international · 2025Article
- Relationships of serum MMP-7 and clinical characteristics in choledochal cyst children.BMC surgery · 2024Article
- The timing of minimally invasive surgery for prenatally diagnosed choledochal cysts.BMC pediatrics · 2024Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEctopic distal location of papilla of Vater (EDLPV) is an obvious pathological feature of choledochal cyst (CDC). This study aimed to investigate the correlation between EDLPV and clinical characteristics of CDCs.
methodsThree groups were studied: Group 1 (G1), papilla in the middle third of second part of duodenum (n = 38); Group 2 (G2), papilla from the distal third of second part to the beginning of third part of duodenum (n = 168); Group 3 (G3), papilla from the middle of third part to fourth part of duodenum (n = 121). Relative variables among three groups were compared.
resultsCompared with G1 and G2, G3 patients had the largest cysts (relative diameter: 1.18 vs. 1.60 vs. 2.62, p < 0.001), the youngest age (20.52 vs. 19.47 vs. -3.40 months, p < 0.001), the highest rate of prenatal diagnosis (26.32% vs. 36.31% vs. 62.81%, p < 0.001), the lowest occurrence of protein plugs in common channel (44.74% vs. 38.69% vs. 16.53%, p < 0.001), and the most elevated total bilirubin level (7.35 vs. 9.95 vs. 28.70 μmol/L, p < 0.001). Prenatally diagnosed G3 patients had heavier liver fibrosis than G2 (13.16% vs. 1.67%, p = 0.015).
conclusionThe more distal papilla location, the more severe clinical characteristics of CDCs, suggesting a crucial role in its pathogenesis.
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