Evidence map›Paper›PMID 37191875›Full record

ArticleJournal of applied clinical medical physics2023

A virtual audit system for intensity-modulated radiation therapy credentialing in Japan Clinical Oncology Group clinical trials: A pilot study.

Mitsuhiro Nakamura, Dejun Zhou, Toshiyuki Minemura, Satoshi Kito, Hiroyuki Okamoto, Naoki Tohyama, Masahiko Kurooka, Yu Kumazaki, Masayori Ishikawa, Catharine H Clark and 7 more

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Mitsuhiro NakamuraDepartment of Advanced Medical Physics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Dejun ZhouDepartment of Advanced Medical Physics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID https://orcid.org/0000-0002-2705-8603
Toshiyuki MinemuraInstitute for Cancer Control, National Cancer Center, Tokyo, Japan.
Satoshi KitoDepartment of Radiation Oncology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan.
Hiroyuki OkamotoRadiation Safety and Quality Assurance Division, National Cancer Center Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9491-787X
Naoki TohyamaDivision of Medical Physics, Tokyo Bay Makuhari Clinic for Advanced Imaging, Cancer Screening, and High-Precision Radiotherapy, Chiba, Japan.
Masahiko KurookaDepartment of Radiation Therapy, Tokyo Medical University Hospital, Tokyo, Japan.
Yu KumazakiDepartment of Radiation Oncology, International Medical Center, Saitama Medical University, Saitama, Japan.
Masayori IshikawaFaculty of Health Sciences, Hokkaido University, Hokkaido, Japan.ORCID https://orcid.org/0000-0003-0317-0200
Catharine H ClarkNational Radiotherapy Trials Quality Assurance (RTTQA) Group, Royal Surrey NHS Foundation Trust, London, UK.
Elizabeth MilesNational Radiotherapy Trials Quality Assurance (RTTQA) Group, Mount Vernon Cancer Centre, Northwood, UK.
Joerg LehmannTrans Tasman Radiation Oncology Group (TROG), Newcastle, Australia.
Nicolaus AndratschkeDepartment of Radiation Oncology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Stephen KryImaging and Radiation Oncology Core (IROC), The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Satoshi IshikuraDivision of Radiation Oncology, Tokyo Bay Makuhari Clinic for Advanced Imaging, Cancer Screening, and High-Precision Radiotherapy, Chiba, Japan.
Takashi MizowakiDepartment of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID https://orcid.org/0000-0002-8135-8746
Teiji NishioMedical Physics Laboratory, Division of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan.

Funding

Grant-in-Aid for Fostering Joint International Research (B) JP18KK0240National Cancer Center Research and Development Fund 2020-J-3
6 · The paper itself

Abstract

purposeThe Medical Physics Working Group of the Radiation Therapy Study Group at the Japan Clinical Oncology Group is currently developing a virtual audit system for intensity-modulated radiation therapy dosimetry credentialing. The target dosimeters include films and array detectors, such as ArcCHECK (Sun Nuclear Corporation, Melbourne, Florida, USA) and Delta4 (ScandiDos, Uppsala, Sweden). This pilot study investigated the feasibility of our virtual audit system using previously acquired data.

methodsWe analyzed 46 films (32 and 14 in the axial and coronal planes, respectively) from 29 institutions. Global gamma analysis between measured and planned dose distributions used the following settings: 3%/3 mm criteria (the dose denominator was 2 Gy), 30% threshold dose, no scaling of the datasets, and 90% tolerance level. In addition, 21 datasets from nine institutions were obtained for array evaluation. Five institutions used ArcCHECK, while the others used Delta4. Global gamma analysis was performed with 3%/2 mm criteria (the dose denominator was the maximum calculated dose), 10% threshold dose, and 95% tolerance level. The film calibration and gamma analysis were conducted with in-house software developed using Python (version 3.9.2).

resultsThe means ± standard deviations of the gamma passing rates were 99.4 ± 1.5% (range, 92.8%-100%) and 99.2 ± 1.0% (range, 97.0%-100%) in the film and array evaluations, respectively.

conclusionThis pilot study demonstrated the feasibility of virtual audits. The proposed virtual audit system will contribute to more efficient, cheaper, and more rapid trial credentialing than on-site and postal audits; however, the limitations should be considered when operating our virtual audit system.

Indexed as

Radiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedCredentialingHumansJapanMedical OncologyPhantoms, ImagingPilot ProjectsRadiometryRadiotherapy Dosagegamma analysisIMRT dosimetry credentialingJCOGprospective trialsvirtual audit

Identifiers

PMID37191875
PMCPMC10243313

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.