Evidence map›Paper›PMID 37191518›Full record

ArticleMicrobiology spectrum2023

Using Genomics To Investigate an Outbreak of Vancomycin-Resistant Enterococcus faecium ST78 at a Large Tertiary Hospital in Queensland.

Budi Permana, Patrick N A Harris, Naomi Runnegar, Margaret Lindsay, Belinda C Henderson, E G Playford, David L Paterson, Scott A Beatson, Brian M Forde

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Genomic epidemiology ofJournal of clinical microbiology · 2026
    Observational
  3. Review
  4. Article
  5. Clinical and microbiological profile of Enterococcus faecium infections in Mexican pediatric patients of a third-level hospital.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  6. Review
  7. Article
  8. Whole-genome sequencing surveillance of vancomycin-resistantInfection control and hospital epidemiology · 2025
    Article
  9. Article
  10. Deciphering vancomycin resistance inFrontiers in microbiology · 2025
    Article
  11. Molecular Characterization of Linezolid-Non-SusceptibleInfection and drug resistance · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Budi PermanaSchool of Chemistry and Molecular Biosciences, Faculty of Science, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-9953-113X
Patrick N A HarrisAustralian Infectious Disease Research Centre, Faculty of Science, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-2895-0345
Naomi RunnegarPrincess Alexandra-Southside Clinical School, Faculty of Medicine, The University of Queensland, Brisbane, Australia.ORCID 0000-0003-1196-4131
Margaret LindsayInfection Management Services, Princess Alexandra Hospital, Brisbane, Australia.
Belinda C HendersonInfection Management Services, Princess Alexandra Hospital, Brisbane, Australia.
E G PlayfordInfection Management Services, Princess Alexandra Hospital, Brisbane, Australia.
David L PatersonUniversity of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia.ORCID 0000-0003-2079-4437
Scott A BeatsonSchool of Chemistry and Molecular Biosciences, Faculty of Science, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-1806-3283
Brian M FordeAustralian Infectious Disease Research Centre, Faculty of Science, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-2264-4785
The University of Queensland · AUPrincess Alexandra Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate an outbreak of vancomycin-resistant Enterococcus faecium (VREfm) sequence type 78 (ST78) in a large tertiary Australian hospital. A collection of 63 VREfm ST78 isolates, identified during a routine genomic surveillance program, were subjected to genomic epidemiological analysis based on whole-genome sequencing (WGS) data. The population structure was reconstructed using phylogenetic analysis, and a collection of publicly available VREfm ST78 genomes were used to provide global context. Core genome single nucleotide polymorphism (SNP) distances and available clinical metadata were used to characterize outbreak clusters and reconstruct transmission events.

Indexed as

Cross InfectionEnterococcus faeciumGram-Positive Bacterial InfectionsVancomycin-Resistant EnterococciAustraliaDisease OutbreaksGenomicsHumansPhylogenyQueenslandTertiary Care CentersVancomycinVancomycinEnterococcusEnterococcus faeciumepidemiologygenomic epidemiologygenomicsoutbreakST78surveillancetransmissionvancomycin resistanceVREwhole-genome sequencing

Identifiers

PMID37191518
PMCPMC10269735
OpenAlexW4376641708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.