Evidence map›Paper›PMID 37191411›Full record

ArticleAging and disease2023

KRT5

Manuel Moreno-Valladares, Veronica Moncho-Amor, Tulio M Silva, Juan P Garcés, María Álvarez-Satta, Ander Matheu

Open access · goldAbstract read
In one paragraph

Article in Aging and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Manuel Moreno-ValladaresBiodonostia Health Research Institute, Group of Cellular Oncology, San Sebastian, Spain.
Veronica Moncho-AmorBiodonostia Health Research Institute, Group of Cellular Oncology, San Sebastian, Spain.
Tulio M SilvaDonostia University Hospital, Pathology Department, San Sebastian, Spain.
Juan P GarcésDonostia University Hospital, Pathology Department, San Sebastian, Spain.
María Álvarez-SattaBiodonostia Health Research Institute, Group of Cellular Oncology, San Sebastian, Spain.
Ander MatheuBiodonostia Health Research Institute, Group of Cellular Oncology, San Sebastian, Spain.
Biogipuzkoa Health Research Institute · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult lungs present high cellular plasticity against stress and injury, mobilizing stem/progenitor populations from conducting airways to maintain tissue homeostasis and gas exchange in alveolar spaces. With aging, pulmonary functional and structural deterioration occurs, mainly in pathological conditions, which is associated with impaired stem cell activity and increased senescence in mice. However, the impact of these processes underlying lung physiopathology in relation to aging has not been explored in humans. In this work, we analyzed stem cell (SOX2, p63, KRT5), senescence (p16

Identifiers

PMID37191411
PMCPMC10187699
OpenAlexW4360597936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.