Evidence map›Paper›PMID 37191331›Full record

Trial reportThe British journal of radiology2023

Two-year follow-up of participants in the BreastScreen Victoria pilot trial of tomosynthesis versus mammography: breast density-stratified screening outcomes.

Nehmat Houssami, Darren Lockie, Michelle Giles, Naomi Noguchi, Georgina Marr, M Luke Marinovich

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nehmat HoussamiThe Daffodil Centre, the University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.
Darren LockieMaroondah BreastScreen, Eastern Health, Victoria, Australia.
Michelle GilesMaroondah BreastScreen, Eastern Health, Victoria, Australia.
Naomi NoguchiSydney School of Public Health, Faculty of Medicine & Health, University of Sydney, Sydney, Australia.
Georgina MarrBreastScreen Victoria, Victoria, Australia.
M Luke MarinovichThe Daffodil Centre, the University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.
Breastscreen Victoria · AUCancer Council NSW · AUEastern Health · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis follow-up study of BreastScreen Victoria's pilot trial of digital breast tomosynthesis aimed to report interval cancer rates, screening sensitivity, and density-stratified outcomes for tomosynthesis

methodsProspective pilot trial [ACTRN-12617000947303] in Maroondah BreastScreen recruited females ≥ 40 years presenting for screening (August 2017-November 2018) to DBT; concurrent screening participants who received mammography formed a comparison group. Follow-up of 24 months from screen date was used to ascertain interval cancers; automated breast density was measured.

resultsThere were 48 screen-detected and 9 interval cancers amongst 4908 tomosynthesis screens, and 34 screen-detected and 16 interval cancers amongst 5153 mammography screens. Interval cancer rate was 1.8/1000 (95%CI 0.8-3.5) for tomosynthesis

conclusionAlthough interval cancer rates did not significantly differ between screened groups, sensitivity was significantly higher for tomosynthesis than mammography screening. ADVANCES IN KNOWLEDGE: In a program-embedded pilot trial, both increased cancer detection and recall rates from tomosynthesis were predominantly observed in high-density screens.

Indexed as

Breast NeoplasmsNeoplasmsAdultBreast DensityEarly Detection of CancerFemaleFollow-Up StudiesHumansMammographyMass ScreeningMiddle AgedPilot ProjectsProspective Studies

Identifiers

PMID37191331
PMCPMC10392654
OpenAlexW4376642351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.