ArticleChemPlusChem2023
5-Nitrofuryl-Containing Thiosemicarbazone Gold(I) Compounds: Synthesis, Stability Studies, and Anticancer Activity.
Esteban Rodríguez-Arce, Eric Gavrilov, Ximena Alvite, Nazia Nayeem, Ignacio E León, Michelle C Neary, Lucía Otero, Dinorah Gambino, Claudio Olea Azar, María Contel
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In one paragraphArticle in ChemPlusChem, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
10 authors.
Esteban Rodríguez-ArceDepartamento de Química Inorgánica y Analítica, Universidad de Chile, Casilla 233, Santiago, Chile.
Eric GavrilovDepartment of Chemistry and Brooklyn College Cancer Center, Brooklyn College, The City University of New York, Brooklyn, NY, 11210, USA.
Ximena AlviteÁrea Química Inorgánica, Facultad de Química, Universidad de la República, Gral. Flores 2124, 11800, Montevideo, Uruguay.
Nazia NayeemDepartment of Chemistry and Brooklyn College Cancer Center, Brooklyn College, The City University of New York, Brooklyn, NY, 11210, USA.ORCID 0000-0001-6733-6965 Ignacio E LeónDepartment of Chemistry and Brooklyn College Cancer Center, Brooklyn College, The City University of New York, Brooklyn, NY, 11210, USA.ORCID 0000-0003-1010-3997 Michelle C NearyChemistry Department, Hunter College, The City University of New York, New York, NY, 10065, USA.ORCID 0000-0003-2805-3668 Lucía OteroÁrea Química Inorgánica, Facultad de Química, Universidad de la República, Gral. Flores 2124, 11800, Montevideo, Uruguay.ORCID 0000-0002-3569-1660 Dinorah GambinoÁrea Química Inorgánica, Facultad de Química, Universidad de la República, Gral. Flores 2124, 11800, Montevideo, Uruguay.ORCID 0000-0001-8678-7374 Claudio Olea AzarDepartamento de Química Inorgánica y Analítica, Universidad de Chile, Casilla 233, Santiago, Chile.
María ContelDepartment of Chemistry and Brooklyn College Cancer Center, Brooklyn College, The City University of New York, Brooklyn, NY, 11210, USA.ORCID 0000-0002-9825-4441 Funding
Biodegradable nanocarriers and antibodies as targeting delivery vehicles for cancer metallodrugsSC1GM127278 · NIGMS · BROOKLYN COLLEGE · PI CONTEL, MARIA · 2018 to 2021
$1.6MNIGMS NIH HHS SC1 GM127278
6 · The paper itselfAbstract
This work describes the synthesis of four gold(I) [AuClL] compounds containing chloro and biologically active protonated thiosemicarbazones based on 5-nitrofuryl (L=HSTC). The stability of the compounds in dichloromethane, DMSO, and DMSO/culture media solutions was investigated by spectroscopy, cyclic voltammetry, and conductimetry, indicating the formation overtime of cationic monometallic [Au(HTSC)(DMSO)]
Indexed as
Antineoplastic AgentsThiosemicarbazonesCell Line, TumorDimethyl SulfoxideGoldAntineoplastic AgentsDimethyl SulfoxideGoldThiosemicarbazonesantitumor agentscytotoxicitygoldmedicinal chemistrythiosemicarbazones
Identifiers
PMID37191319
PMCPMC10651801
What OpenQuestion holds
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