Evidence map›Paper›PMID 37191057›Full record

ArticleEpigenomics2023

The link between 5-hydroxymethylcytosine and DNA demethylation in early embryos.

Gerd P Pfeifer, Piroska E Szabó

Open access · greenAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gerd P PfeiferDepartment of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.ORCID 0000-0002-5080-9604
Piroska E SzabóDepartment of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.ORCID 0000-0001-9314-7009
Van Andel Institute · US

Funding

A Novel Process Safeguards Genome Integrity In The Mammalian Germ Line-Administrative Supplement to Support Undergraduate Summer Research ExperiencesR01GM143308 · NIGMS · VAN ANDEL RESEARCH INSTITUTE · PI SZABÓ, PIROSKA EDIT · 2022 to 2025
$2.1M
5-methylcytosine oxidation in development and diseaseR01AR079174 · NIAMS · VAN ANDEL RESEARCH INSTITUTE · PI PFEIFER, GERD P · 2021 to 2025
$2.1M
NIAMS NIH HHS R01 AR079174NIGMS NIH HHS R01 GM143308
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

5-MethylcytosineDNA DemethylationDNA MethylationEmbryonic DevelopmentHumans5-hydroxymethylcytosine5-Methylcytosine5-hydroxymethylcytosineACE-seqepiblastgenome-wide DNA demethylationglobal reprogrammingH3K9me2Nlrp14 knockoutTET3Tet3 conditional knockoutzygote

Identifiers

PMID37191057
PMCPMC10242432
OpenAlexW4376642811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.