Evidence map›Paper›PMID 37190767›Full record

ArticleMolecules and cells2023

Wnt/β-Catenin Signaling Pathway Is Necessary for the Specification but Not the Maintenance of the Mouse Retinal Pigment Epithelium.

Jong-Myeong Kim, Kwang Wook Min, You-Joung Kim, Ron Smits, Konrad Basler, Jin Woo Kim

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Jong-Myeong KimDepartment of Biological Sciences and KAIST Stem Cell Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0001-5204-1312
Kwang Wook MinDepartment of Biological Sciences and KAIST Stem Cell Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0002-7593-7047
You-Joung KimDepartment of Biological Sciences and KAIST Stem Cell Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0003-4089-8292
Ron SmitsDepartment of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-6798-3206
Konrad BaslerDepartment of Molecular Life Sciences, University of Zurich, CH-8057 Zurich, Switzerland.ORCID https://orcid.org/0000-0003-3534-1529
Jin Woo KimDepartment of Biological Sciences and KAIST Stem Cell Center, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0003-0767-1918
Korea Advanced Institute of Science and Technology · KRErasmus MC · NLUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Catenin (Ctnnb1) has been shown to play critical roles in the development and maintenance of epithelial cells, including the retinal pigment epithelium (RPE). Ctnnb1 is not only a component of intercellular junctions in the epithelium, it also functions as a transcriptional regulator in the Wnt signaling pathway. To identify which of its functional modalities is critically involved in mouse RPE development and maintenance, we varied

Indexed as

Retinal Pigment EpitheliumWnt Signaling PathwayAnimalsbeta CateninCell DifferentiationGene Expression RegulationMiceNeuronsbeta Cateninciliary marginretinaretinal pigment epitheliumWntβ-catenin

Identifiers

PMID37190767
PMCPMC10336276
OpenAlexW4376641154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.