Evidence map›Paper›PMID 37190758›Full record

ArticleJournal of biological rhythms2023

A Cannabinoid Receptor 1 Agonist Reduces Light-induced Phase Delays in Male But Not Female Mice.

Timothy D Niepokny, Eric M Mintz

Open access · greenAbstract read
In one paragraph

Article in Journal of biological rhythms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. A sleepy cannabis constituent: cannabinol and its active metabolite influence sleep architecture in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Timothy D NiepoknyDepartment of Biological Sciences, School of Biomedical Sciences, and Brain Health Research Institute, Kent State University, Kent, Ohio.ORCID 0009-0006-3390-8981
Eric M MintzDepartment of Biological Sciences, School of Biomedical Sciences, and Brain Health Research Institute, Kent State University, Kent, Ohio.ORCID 0000-0003-1775-1129
Kent State University · US

Funding

Regulation of Circadian Rhythms by CannabinoidsR15GM134528 · NIGMS · KENT STATE UNIVERSITY · PI MINTZ, ERIC M · 2019 to 2019
$447k
NIGMS NIH HHS R15 GM134528
6 · The paper itself

Abstract

Animals adapt to a changing environment by synchronizing their circadian rhythms to different stimuli, the strongest and most reliable being the daily light-dark cycle. Photic information reaches the central circadian pacemaker, the suprachiasmatic nucleus (SCN), which drives rhythms in physiology and behavior throughout the brain and body. The endocannabinoid system (ECS) is a neuromodulatory system that is present within the SCN, including the primary receptor, cannabinoid receptor 1 (CB1). Exogenous cannabinoids that target CB1 inhibit the phase-shifting effects of light in hamsters, mice, and rats. Furthermore, there is evidence in cultured microglial cells that cannabidiol (CBD), a constituent of

Indexed as

CannabinoidsCircadian RhythmAnimalsCannabinoid Receptor AgonistsCricetinaeFemaleMaleMiceMice, Inbred C57BLRatsReceptors, CannabinoidSuprachiasmatic NucleusCannabinoid Receptor AgonistsCannabinoidsReceptors, Cannabinoidcannabinoidscircadianentrainmentlight entrainmentlocomotor activitySCNsex differencewheel-running

Identifiers

PMID37190758
PMCPMC10330025
OpenAlexW4376643052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.