Evidence map›Paper›PMID 37190628›Full record

ArticleBrain sciences2023

Improved Biomagnetic Signal-To-Noise Ratio and Source Localization Using Optically Pumped Magnetometers with Synthetic Gradiometers.

Jing Xiang, Xiaoqian Yu, Scott Bonnette, Manish Anand, Christopher D Riehm, Bryan Schlink, Jed A Diekfuss, Gregory D Myer, Yang Jiang

Registry-linked trialAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00600717 (Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00600717 withdrawnnot on this map

Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals

TypeobservationalSponsorChildren's Hospital Medical Center, CincinnatiRan2000 to 2027Enrolled0ConditionsEpilepsy, Migraine, Headache, Pain
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. A Single-Cell Optically Pumped Intrinsic Gradiometer.Sensors (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jing XiangMEG Center, Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0003-0242-5590
Xiaoqian YuLaureate Institute for Brain Research, 6655 S Yale Ave., Tulsa, OK 74136, USA.ORCID 0000-0003-4652-3707
Scott BonnetteDivision of Sports Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-4002-6286
Manish AnandEmory Sport Performance and Research Center (SPARC), Emory University, Flowery Branch, GA 30542, USA.
Christopher D RiehmEmory Sport Performance and Research Center (SPARC), Emory University, Flowery Branch, GA 30542, USA.
Bryan SchlinkEmory Sport Performance and Research Center (SPARC), Emory University, Flowery Branch, GA 30542, USA.
Jed A DiekfussEmory Sport Performance and Research Center (SPARC), Emory University, Flowery Branch, GA 30542, USA.
Gregory D MyerEmory Sport Performance and Research Center (SPARC), Emory University, Flowery Branch, GA 30542, USA.
Yang JiangDepartment of Behavioral Science, University of Kentucky College of Medicine, Lexington, KY 40536, USA.

Funding

Predictive Neurophysiological Biomarkers for Risk of Alzheimer’s Disease (AD) and Related Dementia (ADRD) Induced Cognitive Impairment in Sino-US CohortsR56AG060608 · NIA · UNIVERSITY OF KENTUCKY · PI JIANG, YANG · 2018 to 2018
$440k
NIA NIH HHS R56 AG060608
6 · The paper itself

Abstract

Optically pumped magnetometers (OPMs) can capture brain activity but are susceptible to magnetic noise. The objective of this study was to evaluate a novel methodology used to reduce magnetic noise in OPM measurements. A portable magnetoencephalography (MEG) prototype was developed with OPMs. The OPMs were divided into primary sensors and reference sensors. For each primary sensor, a synthetic gradiometer (SG) was constructed by computing a secondary sensor that simulated noise with signals from the reference sensors. MEG data from a phantom with known source signals and six human participants were used to assess the efficacy of the SGs. Magnetic noise in the OPM data appeared predominantly in a low frequency range (<4 Hz) and varied among OPMs. The SGs significantly reduced magnetic noise (

Indexed as

magnetoencephalographynoise cancellationoptically pumped magnetometersignal-to-noise ratiosynthetic gradiometerwearable MEG

Identifiers

PMID37190628
PMCPMC10136792

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.