Evidence map›Paper›PMID 37190534›Full record

ReviewBrain sciences2023

Sleep Deprivation and Insomnia in Adolescence: Implications for Mental Health.

Sara Uccella, Ramona Cordani, Federico Salfi, Maurizio Gorgoni, Serena Scarpelli, Angelo Gemignani, Pierre Alexis Geoffroy, Luigi De Gennaro, Laura Palagini, Michele Ferrara and 1 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06551428 (The Sleep Stress Connection), which is not on this map. Cited by 72 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06551428 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Sleep Stress Connection: Investigating How Sleep Quality Affects Mental and Physical Health

Typeobservational_patient_registrySponsorAhmed Ali Mohammed ToradRan2025 to 2025Enrolled380ConditionsMental Health Issue, Physical Stress
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  16. Social Rhythms, Depressive Symptoms, and Quality of Life: An Unbreakable Bond in an Older Adult Sample.International journal of environmental research and public health · 2026
    Observational
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara UccellaDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0003-4164-2125
Ramona CordaniDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16126 Genoa, Italy.
Federico SalfiDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0003-1961-286X
Maurizio GorgoniDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-5544-5483
Serena ScarpelliDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-9260-7111
Angelo GemignaniDepartment of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Azienda Ospedaliera Universitaria Pisana AUOP, 56126 Pisa, Italy.
Pierre Alexis GeoffroyDépartement de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat-Claude Bernard, 75018 Paris, France.ORCID 0000-0001-9121-209X
Luigi De GennaroDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-3613-6631
Laura PalaginiPsychiatric Clinic, Department of Clinical and Experimental Medicine, Azienda Ospedaliero Universitaria Pisana AUOP, 56126 Pisa, Italy.
Michele FerraraDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0003-2304-7576
Lino NobiliDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16126 Genoa, Italy.

Funding

This work was supported by the Italian Ministry of Health, 5 x 1000 project 2017, "SOLAR: Sleep disorders in children: an innovative clinical research perspective". This study was conducted as part of the MNESYS research and innovation program (A multisca 5 x 1000 project 2017; Piano Nazionale di Ripresa e Resilienza (PNRR).
6 · The paper itself

Abstract

Sleep changes significantly throughout the human lifespan. Physiological modifications in sleep regulation, in common with many mammals (especially in the circadian rhythms), predispose adolescents to sleep loss until early adulthood. Adolescents are one-sixth of all human beings and are at high risk for mental diseases (particularly mood disorders) and self-injury. This has been attributed to the incredible number of changes occurring in a limited time window that encompasses rapid biological and psychosocial modifications, which predispose teens to at-risk behaviors. Adolescents' sleep patterns have been investigated as a biunivocal cause for potential damaging conditions, in which insufficient sleep may be both a cause and a consequence of mental health problems. The recent COVID-19 pandemic in particular has made a detrimental contribution to many adolescents' mental health and sleep quality. In this review, we aim to summarize the knowledge in the field and to explore implications for adolescents' (and future adults') mental and physical health, as well as to outline potential strategies of prevention.

Indexed as

adolescencecircadian rhythmsCOVID-19insomniamental healthmood disorderspsychiatric disorderssleep

Identifiers

PMID37190534
PMCPMC10136689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.