ArticleBrain sciences2023
Longitudinal Coupling between Eating Disorder Psychopathology and Depression in Patients with Anorexia Nervosa and Bulimia Nervosa Treated with Enhanced Cognitive Behavior Therapy: A One-Year Follow-Up Study.
Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biological treatments for co-occurring eating disorders and psychological trauma: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Developing a Clinical Prediction Model for Nonimprovement of Depressive Symptoms at Discharge After Treatment of Eating Disorders.The International journal of eating disorders · 2026Article
- Feasibility and clinical outcomes of tailored digital CBT-E guided self-help for youth with binge-eating symptoms: A pilot randomized controlled trial.Internet interventions · 2026Article
- Mapping the path to recovery: the intersection of cortical thickness reductions and serotonin transporter expression in anorexia nervosa.Molecular psychiatry · 2026Article
- Eating disorder symptoms and corresponding evidence-based treatments: a narrative review.Journal of eating disorders · 2026Review
- Adiponectin and gastric fundus: A potential target for gut-brain axis dysfunctions.Physiological reports · 2025Review
- Identification of Genes in Diagnosing Major Depressive Disorder with Anorexia Through Bioinformatics Analysis.Neuropsychiatric disease and treatment · 2025Article
- Gut microbiota and inflammatory factor characteristics in major depressive disorder patients with anorexia.BMC psychiatry · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between eating disorder (ED) specific psychopathology and depressive symptomatology in EDs is often debated. The aim of this study was to provide an explicative model regarding the mechanisms by which enhanced cognitive-behavior therapy (CBT-E) might determine an amelioration of depressive symptoms in patients with anorexia nervosa (AN) or bulimia nervosa (BN).
methodsA total of 157 women with AN or BN and no history of childhood trauma or bipolar disorder were evaluated before treatment and after 12 months of CBT-E. Self-administered questionnaires were used to measure ED psychopathology and depressive symptoms.
resultsAll psychopathological measures improved after treatment, with no significant additional improvement with the concomitant use of antidepressants. Structural equation modeling using the bivariate latent change score approach showed that higher levels of depressive symptoms at baseline were associated with a worse longitudinal trend of ED psychopathology, and vice versa. Finally, the amelioration of ED psychopathology predicted the improvement in depressive symptoms at follow-up, whereas data did not support the inverse path.
conclusionThis study elucidated the complex longitudinal interplay between ED psychopathology and depression during CBT-E, underlining the importance of addressing ED symptoms as a primary target in the case of comorbidity between AN or BN and depressive symptoms.
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