Evidence map›Paper›PMID 37190329›Full record

ArticleCancers2023

Pterostilbene and Probiotic Complex in Chemoprevention of Putative Precursor Lesions for Colorectal Cancer in an Experimental Model of Intestinal Carcinogenesis with 1,2-Dimethylhydrazine.

Márcio Alencar Barreira, Márcio Wilker Soares Campelo, Conceição da Silva Martins Rebouças, Antoniella Souza Gomes Duarte, Maria Lucianny Lima Barbosa, Said Gonçalves da Cruz Fonseca, Raphaela Ribeiro Queiroz, Érica Uchoa Holanda, Ana Beatriz Aragão de Vasconcelos, Vitória Jannyne Guimarães de Sousa Araújo and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Progress on the mechanism of intestinal microbiota against colorectal cancer.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Márcio Alencar BarreiraWalter Cantídio University Hospital, Federal University of Ceará, Fortaleza 60430-140, CE, Brazil.ORCID 0000-0001-6459-8732
Márcio Wilker Soares CampeloDepartment of Surgery, School of Medicine, Federal University of Ceará, Fortaleza 60430-140, CE, Brazil.
Conceição da Silva Martins RebouçasLaboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, School of Medicine, Federal University of Ceará, Fortaleza 60430-170, CE, Brazil.
Antoniella Souza Gomes DuarteLaboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, School of Medicine, Federal University of Ceará, Fortaleza 60430-170, CE, Brazil.
Maria Lucianny Lima BarbosaLaboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, School of Medicine, Federal University of Ceará, Fortaleza 60430-170, CE, Brazil.
Said Gonçalves da Cruz FonsecaDepartment of Pharmacy, School of Pharmacy, Federal University of Ceará, Fortaleza 60430-370, CE, Brazil.
Raphaela Ribeiro QueirozSchool of Medicine, Christus University Center (UNICHRISTUS), Fortaleza 60192-345, CE, Brazil.
Érica Uchoa HolandaSchool of Medicine, Christus University Center (UNICHRISTUS), Fortaleza 60192-345, CE, Brazil.ORCID 0000-0002-0759-5567
Ana Beatriz Aragão de VasconcelosSchool of Medicine, Christus University Center (UNICHRISTUS), Fortaleza 60192-345, CE, Brazil.
Vitória Jannyne Guimarães de Sousa AraújoSchool of Medicine, Christus University Center (UNICHRISTUS), Fortaleza 60192-345, CE, Brazil.
Gabriel Maia DinizSchool of Medicine, Christus University Center (UNICHRISTUS), Fortaleza 60192-345, CE, Brazil.
Reinaldo Barreto OriáLaboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, School of Medicine, Federal University of Ceará, Fortaleza 60430-170, CE, Brazil.
Paulo Roberto Leitão de VasconcelosDepartment of Surgery, School of Medicine, Federal University of Ceará, Fortaleza 60430-140, CE, Brazil.
Universidade Federal do Ceará · BRUnichristus · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary supplementation with pterostilbene (PS) and/or a probiotic (PRO) may ameliorate the intestinal microbiota in disease conditions. This study aims to evaluate PS and PRO for the chemoprevention of putative precursor lesions for colorectal cancer (CRC) in an experimental model of intestinal carcinogenesis with 1,2-dimethylhydrazine (1,2-DMH). Sixty male Wistar rats were equally divided into five groups: Sham, 1,2-DMH, 1,2-DMH + PS, 1,2-DMH + PRO, and 1,2-DMH + PS + PRO. PRO (5 × 10

Indexed as

aberrant crypt focicarcinogenesischemopreventioncolorectal neoplasmsintestinal inflammationintestinal microbiotaprobioticspterostilbeneWnt signaling pathway

Identifiers

PMID37190329
PMCPMC10136993
OpenAlexW4366773926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.