Evidence map›Paper›PMID 37190328›Full record

ReviewCancers2023

The Role of AI in Breast Cancer Lymph Node Classification: A Comprehensive Review.

Josip Vrdoljak, Ante Krešo, Marko Kumrić, Dinko Martinović, Ivan Cvitković, Marko Grahovac, Josip Vickov, Josipa Bukić, Joško Božic

Abstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. The Evolution and Clinical Impact of Deep Learning Technologies in Breast MRI.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Josip VrdoljakDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.
Ante KrešoDepartment of Surgery, University Hospital of Split, 21000 Split, Croatia.
Marko KumrićDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0002-9696-3359
Dinko MartinovićDepartment of Surgery, University Hospital of Split, 21000 Split, Croatia.ORCID 0000-0003-2060-5130
Ivan CvitkovićDepartment of Surgery, University Hospital of Split, 21000 Split, Croatia.
Marko GrahovacDepartment of Pharmacology, University of Split School of Medicine, 21000 Split, Croatia.
Josip VickovDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.
Josipa BukićDepartment of Pharmacy, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0002-9316-5538
Joško BožicDepartment of Pathophysiology, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0003-1634-0635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is a significant health issue affecting women worldwide, and accurately detecting lymph node metastasis is critical in determining treatment and prognosis. While traditional diagnostic methods have limitations and complications, artificial intelligence (AI) techniques such as machine learning (ML) and deep learning (DL) offer promising solutions for improving and supplementing diagnostic procedures. Current research has explored state-of-the-art DL models for breast cancer lymph node classification from radiological images, achieving high performances (AUC: 0.71-0.99). AI models trained on clinicopathological features also show promise in predicting metastasis status (AUC: 0.74-0.77), whereas multimodal (radiomics + clinicopathological features) models combine the best from both approaches and also achieve good results (AUC: 0.82-0.94). Once properly validated, such models could greatly improve cancer care, especially in areas with limited medical resources. This comprehensive review aims to compile knowledge about state-of-the-art AI models used for breast cancer lymph node metastasis detection, discusses proper validation techniques and potential pitfalls and limitations, and presents future directions and best practices to achieve high usability in real-world clinical settings.

Indexed as

AIartificial intelligencebreast cancerclinicopathological featuresdeep learninglymph node classificationmachine learningradiomics

Identifiers

PMID37190328
PMCPMC10137197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.