Evidence map›Paper›PMID 37190273›Full record

ArticleCancers2023

Theranostics of Primary Prostate Cancer: Beyond PSMA and GRP-R.

Romain Schollhammer, Marie-Laure Quintyn Ranty, Henri de Clermont Gallerande, Florine Cavelier, Ibai E Valverde, Delphine Vimont, Elif Hindié, Clément Morgat

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03604757 (Exploratory, Single-institution Study, Comparing 68Ga-RM2 PET/CT Versus 68Ga-PSMA-617 PET/CT in Patients Diagnosed With Prostate Cancer of Various Metastatic Risks Candidates for Radical Prostatectomy - "UROPET"), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03604757 phase2completednot on this map

Exploratory, Single-institution Study, Comparing 68Ga-RM2 PET/CT Versus 68Ga-PSMA-617 PET/CT in Patients Diagnosed With Prostate Cancer of Various Metastatic Risks Candidates for Radical Prostatectomy - "UROPET"

TypeinterventionalSponsorUniversity Hospital, BordeauxRan2018 to 2019Enrolled22ConditionsProstate CancerArms68Ga-PSMA-617 PET/CT, 68Ga-RM2 PET/CT
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Design and Synthesis ofChemMedChem · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Neurotensin and Its Involvement in Female Hormone-Sensitive Cancers.International journal of molecular sciences · 2024
    Review
  6. Two Novel [ACS omega · 2024
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Romain SchollhammerNuclear Medicine Department, Bordeaux University Hospital, 33000 Bordeaux, France.
Marie-Laure Quintyn RantyDepartment of Pathology, University Hospital of Toulouse, 31000 Toulouse, France.
Henri de Clermont GallerandeNuclear Medicine Department, Bordeaux University Hospital, 33000 Bordeaux, France.
Florine CavelierInstitut des Biomolécules Max Mousseron IBMM, UMR 5247, CNRS, Université Montpellier, ENSCM, Pôle Chimie Balard, 1919 Route de Mende, Cedex 5, 34293 Montpellier, France.ORCID 0000-0001-5308-6416
Ibai E ValverdeInstitut de Chimie Moléculaire de l'Université de Bourgogne, UMR 6302, CNRS, Université Bourgogne Franche-Comté, 9 Avenue Alain Savary, 21000 Dijon, France.ORCID 0000-0002-5802-4131
Delphine VimontINCIA, University of Bordeaux, CNRS, EPHE, UMR 5287, 33000 Bordeaux, France.
Elif HindiéNuclear Medicine Department, Bordeaux University Hospital, 33000 Bordeaux, France.
Clément MorgatNuclear Medicine Department, Bordeaux University Hospital, 33000 Bordeaux, France.ORCID 0000-0002-9432-9223
Centre National de la Recherche Scientifique · FRÉcole Nationale Supérieure de Chimie de Montpellier · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FR

Funding

INCa-canceropole GSO 2020-E19ITMO Cancer of Aviesan 22CP154-00
6 · The paper itself

Abstract

The imaging of Prostate-Specific Membrane Antigen (PSMA) is now widely used at the initial staging of prostate cancers in patients with a high metastatic risk. However, its ability to detect low-grade tumor lesions is not optimal.

methodsFirst, we prospectively performed neurotensin receptor-1 (NTS

resultsIn the IHC study, all samples with negative PSMA staining (two patients with ISUP 2 and one with ISUP 3) were strongly positive for NTS

conclusionsTargeting PSMA and NTS

Indexed as

GRP-RneuropeptideneurotensinNTS1NTS2prostate cancerPSMA

Identifiers

PMID37190273
PMCPMC10137308
OpenAlexW4366286928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.