Evidence map›Paper›PMID 37190160›Full record

ArticleCancers2023

Integrated Microbiota and Metabolite Changes following Rice Bran Intake during Murine Inflammatory Colitis-Associated Colon Cancer and in Colorectal Cancer Survivors.

Annika M Weber, Hend Ibrahim, Bridget A Baxter, Robin Kumar, Akhilendra K Maurya, Dileep Kumar, Rajesh Agarwal, Komal Raina, Elizabeth P Ryan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01929122 (BENEFIT), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01929122 nacompletednot on this map

BENEFIT: Beans/Bran Enriching Nutritional Eating For Intestinal Health Trial

TypeinterventionalSponsorColorado State UniversityRan2010 to 2014Enrolled29ConditionsColorectal Cancer Control and PreventionArmsPlacebo-Control Meals and Snacks, Cooked Navy Bean Powder Meals and Snacks, Rice Bran Meals and Snacks
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Annika M WeberDepartment of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0002-7234-879X
Hend IbrahimDepartment of Medical Biochemistry, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0002-6807-9718
Bridget A BaxterDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Robin KumarDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA.ORCID 0000-0002-6531-2035
Akhilendra K MauryaDepartment of Pharmaceutical Sciences, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-5107-9546
Dileep KumarDepartment of Pharmaceutical Sciences, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-9978-9950
Rajesh AgarwalDepartment of Pharmaceutical Sciences, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-9455-0235
Komal RainaDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA.ORCID 0000-0003-0371-1070
Elizabeth P RyanDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0002-1577-0919
Colorado State University · USUniversity of Colorado Anschutz Medical Campus · USSouth Dakota State University · USZagazig University · EG

Funding

CSU Infectious Disease Research and Response Training ProgramT32AI162691 · NIAID · COLORADO STATE UNIVERSITY · PI DEAN, GREGG A · 2021 to 2025
$2.1M
Rice Bran Microbial Metabolism for Colon ChemopreventionR01CA201112 · NCI · COLORADO STATE UNIVERSITY · PI RAINA, KOMAL, RYAN, ELIZABETH P · 2016 to 2020
$1.9M
NCI NIH HHS R01 CA201112NIAID NIH HHS T32 AI162691NIH HHS 1R01CA201112-01A1
6 · The paper itself

Abstract

Dietary rice bran-mediated inhibition of colon carcinogenesis was demonstrated previously for carcinogen-induced rodent models via multiple anti-cancer mechanisms. This study investigated the role of dietary rice bran-mediated changes to fecal microbiota and metabolites over the time course of colon carcinogenesis and compared murine fecal metabolites to human stool metabolic profiles following rice bran consumption by colorectal cancer survivors (NCT01929122). Forty adult male BALB/c mice were subjected to azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colitis-associated colon carcinogenesis and randomized to control AIN93M (

Indexed as

AOM/DSScolorectal cancermetabolomemicrobiomerice bran

Identifiers

PMID37190160
PMCPMC10136752
OpenAlexW4363676047

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.