General Anesthesia in Early Childhood Significantly Reduces Asthma Incidence and Clinical Visits: A Nationwide Population-Based Cohort Study.

Ya-Ling Yang, Jung-Chan Chang, Shu-Chen Ho, Chien-Ning Yeh, Ho-Chang Kuo

Open access · goldAbstract read

In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 97% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ya-Ling YangDepartment of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City 833, Taiwan.ORCID 0000-0001-6914-3227

Jung-Chan ChangDepartment of Data Science and Analytics, I-Shou University, Kaohsiung 840, Taiwan.

Shu-Chen HoDepartment of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.

Chien-Ning YehDepartment of Data Science and Analytics, I-Shou University, Kaohsiung 840, Taiwan.

Ho-Chang KuoDepartment of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.ORCID 0000-0002-3295-2984

I-Shou University · TWChang Gung University · TWKaohsiung Chang Gung Memorial Hospital · TWKaohsiung Medical University · TW

Funding

National Science and Technology Council of Taiwan 111-2635-B-182A-009-

6 · The paper itself

Abstract

Few studies have focused on the consequence of exposure to general anesthesia (GA) in children's early life with the risk of asthma and disease outcomes. The present study examines the correlation between exposure to GA under three years old and the subsequent course of asthma in a nationwide population-based cohort study. Our cases were acquired from Taiwan's National Health Insurance Research Database (NHIRD). Children under three years old with either GA exposure or not during in-patient treatment from 1997 to 2008 were included. The study group was age- and sex-matched with a ratio of 1:2 to create the control group for comparison. The cohort included 2261 cases with GA and 4522 cases without GA as a control group. The incidence of asthma onset was significantly reduced in patients with GA exposure under 3 three years old (hazard ratio 0.64 (95% confidence interval 0.57~0.72),

Indexed as

asthmageneral anesthesiaincidenceoutcome

Identifiers

PMID37189875

DOI10.3390/children10040626

PMCPMC10136517

OpenAlexW4361005024

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.