Evidence map›Paper›PMID 37189767›Full record

ArticleBiomedicines2023

Maternal Plasma RNA in First Trimester Nullipara for the Prediction of Spontaneous Preterm Birth ≤ 32 Weeks: Validation Study.

Carl P Weiner, Helen Zhou, Howard Cuckle, Argyro Syngelaki, Kypros H Nicolaides, Mark L Weiss, Yafeng Dong

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Fetal Heart Rate at 12 Weeks' Gestation and the Risk of Preterm Birth: A Prospective Validation Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Carl P WeinerDepartment of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, KS 66160, USA.ORCID 0000-0002-1044-9026
Helen ZhouDepartment of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Howard CuckleFaculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.ORCID 0000-0003-2450-2403
Argyro SyngelakiFetal Medicine Research Institute, King's College Hospital, London SE5 9RS, UK.
Kypros H NicolaidesFetal Medicine Research Institute, King's College Hospital, London SE5 9RS, UK.
Mark L WeissDepartments of Anatomy and Physiology & Midwest Institute of Comparative Stem Cell Biology, Kansas State University, Manhattan, KS 66503, USA.ORCID 0000-0002-4647-7619
Yafeng DongDepartment of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
University of Kansas Medical Center · USKing's College Hospital · GBKansas State University · USTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first-trimester prediction of spontaneous preterm birth (sPTB) has been elusive, and current screening is heavily dependent on obstetric history. However, nullipara lack a relevant history and are at higher risk for spontaneous (s)PTB ≤ 32 weeks compared to multipara. No available objective first-trimester screening test has proven a fair predictor of sPTB ≤ 32 weeks. We questioned whether a panel of maternal plasma cell-free (PCF) RNAs (

Indexed as

plasma transcriptomepregnancypreterm birthscreening tests

Identifiers

PMID37189767
PMCPMC10135717
OpenAlexW4365146518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.