Evidence map›Paper›PMID 37189766›Full record

ArticleBiomedicines2023

PSMA Expression Correlates with Improved Overall Survival and VEGF Expression in Glioblastoma.

Alexander Yuile, Adrian Lee, Elizabeth A Moon, Amanda Hudson, Marina Kastelan, Samuel Miller, David Chan, Joe Wei, Michael F Back, Helen R Wheeler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alexander YuileDepartment of Medical Oncology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW 2065, Australia.ORCID 0000-0002-7242-0528
Adrian LeeDepartment of Medical Oncology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW 2065, Australia.ORCID 0000-0001-5345-5226
Elizabeth A MoonFaculty of Medicine and Health Sciences, Northern Clinical School, The University of Sydney, Sydney, NSW 2000, Australia.
Amanda HudsonFaculty of Medicine and Health Sciences, Northern Clinical School, The University of Sydney, Sydney, NSW 2000, Australia.
Marina KastelanThe Brain Cancer Group, North Shore Private Hospital, Westbourne Street, St Leonards, NSW 2065, Australia.
Samuel MillerDepartment of Medical Oncology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW 2065, Australia.
David ChanDepartment of Medical Oncology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW 2065, Australia.
Joe WeiDepartment of Medical Oncology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW 2065, Australia.
Michael F BackFaculty of Medicine and Health Sciences, Northern Clinical School, The University of Sydney, Sydney, NSW 2000, Australia.
Helen R WheelerDepartment of Medical Oncology, Royal North Shore Hospital, Reserve Road, St Leonards, NSW 2065, Australia.
The University of Sydney · AURoyal North Shore Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlioblastomas are the most common and fatal primary brain malignancy in adults. There is a growing interest in identifying the molecular mechanisms of these tumors to develop novel treatments. Glioblastoma neo-angiogenesis is driven by VEGF, and another potential molecule linked to angiogenesis is PSMA. Our study suggests the potential for an association between PSMA and VEGF expression in glioblastoma neo-vasculature.

methodsArchived

resultsIn total, 247 patients with

conclusionWe found a potential positive correlation between PSMA and VEGF expression. Secondly, we showed a potential positive correlation between PSMA expression and overall survival.

Indexed as

angiogenesisbiomarkerglioblastomaimmunohistochemistryPSMAVEGF

Identifiers

PMID37189766
PMCPMC10135493
OpenAlexW4365146577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.