Evidence map›Paper›PMID 37189708›Full record

ArticleBiomedicines2023

Activated Natural Killer Cell Inoculation Alleviates Fibrotic Liver Pathology in a Carbon Tetrachloride-Induced Liver Cirrhosis Mouse Model.

Ho Rim Oh, Min Kyung Ko, Daehee Son, Young Wook Ki, Shin-Il Kim, Seok-Yong Lee, Keon Wook Kang, Gi Jeong Cheon, Do Won Hwang, Hyewon Youn

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ho Rim OhDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0002-3620-836X
Min Kyung KoResearch & Development Center, THERABEST, Co., Ltd., Seoul 06656, Republic of Korea.
Daehee SonResearch & Development Center, THERABEST, Co., Ltd., Seoul 06656, Republic of Korea.
Young Wook KiResearch & Development Center, THERABEST, Co., Ltd., Seoul 06656, Republic of Korea.
Shin-Il KimResearch & Development Center, THERABEST, Co., Ltd., Seoul 06656, Republic of Korea.ORCID 0000-0002-7350-0087
Seok-Yong LeeDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Keon Wook KangDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0003-2622-9017
Gi Jeong CheonDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Do Won HwangResearch & Development Center, THERABEST, Co., Ltd., Seoul 06656, Republic of Korea.
Hyewon YounDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0003-1006-2689
Seoul National University · KR

Funding

National Research Foundation of Korea 2020R1A2C2011428National Research Foundation of Korea 2022R1F1A1069854National Research Foundation of Korea NRF-2020R1A2C2011695
6 · The paper itself

Abstract

Activated hepatic stellate cells (HSCs) play a detrimental role in liver fibrosis progression. Natural killer (NK) cells are known to selectively recognize abnormal or transformed cells via their receptor activation and induce target cell apoptosis and, therefore, can be used as a potential therapeutic strategy for liver cirrhosis. In this study, we examined the therapeutic effects of NK cells in the carbon tetrachloride (CCl

Indexed as

bioluminescence imaging (BLI)carbon tetrachloride (CCl4)liver cirrhosisnatural killer (NK) cells

Identifiers

PMID37189708
PMCPMC10135902
OpenAlexW4362557415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.