Evidence map›Paper›PMID 37189630›Full record

ArticleBiomedicines2023

Oral Microbiota Signatures in the Pathogenesis of Euthyroid Hashimoto's Thyroiditis.

Mustafa Genco Erdem, Ozge Unlu, Fatma Ates, Denizhan Karis, Mehmet Demirci

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Elimination of oral foci of infection might lead to clinical improvement of Graves' orbitopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Mustafa Genco ErdemDepartment of Internal Medicine, Faculty of Medicine, Beykent University, Istanbul 34398, Turkey.ORCID 0000-0002-7783-8130
Ozge UnluDepartment of Medical Microbiology, Faculty of Medicine, Istanbul Atlas University, İstanbul 34403, Turkey.ORCID 0000-0002-5411-5925
Fatma AtesDepartment of Biophysics, Faculty of Medicine, Beykent University, Istanbul 34398, Turkey.
Denizhan KarisDepartment of Biophysics, Faculty of Medicine, Istinye University, Istanbul 34460, Turkey.ORCID 0000-0002-5976-4107
Mehmet DemirciDepartment of Medical Microbiology, Faculty of Medicine, Kirklareli University, Kirklareli 39100, Turkey.ORCID 0000-0001-9670-2426
Beykent University · TRAtlas ÜniversitesiIstinye University · TRKırklareli University · TR

Funding

Beykent University 2021-2022-BAP-02
6 · The paper itself

Abstract

One of the most prevalent autoimmune illnesses in the world is Hashimoto's thyroiditis, whose pathogenesis is still unknown. The gut-thyroid axis is frequently examined, and although oral health affects thyroid functions, there are limited data on how oral microbiota is linked to Hashimoto's thyroiditis. The study aims to identify the oral microbiota from saliva samples taken from treated (with levothyroxine) and untreated female euthyroid Hashimoto's thyroiditis patients as well as healthy controls who were age- and sex-matched to compare the oral microbiota across the groups and to contribute preliminary data to the literature. This study was designed as a single-center cross-sectional observational study. Sixty (60) female patients with euthyroid Hashimoto's thyroiditis (HT) and eighteen (18) age- and gender-matched healthy controls were included in this study. Unstimulated saliva samples were collected. After DNA isolation, sequencing was performed by targeting the V3-V4 gene regions of the 16S rRNA on the MiSeq instrument. R scripts and SPSS were used for bioinformatic and statistical analysis. No significant differences were found in the diversity indices. However,

Indexed as

autoimmunityHashimoto’s thyroiditisoral microbiota

Identifiers

PMID37189630
PMCPMC10136106
OpenAlexW4361008689

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.