Evidence map›Paper›PMID 37189625›Full record

ArticleBiomedicines2023

Invasive Cutaneous Candidiasis, Autoimmune Hemolytic Anemia and Pancytopenia: A Challenging Scenario for Waldenström Macroglobulinemia in an Elderly Patient.

Juan Carlos Caballero, Elham Askari, Nerea Carrasco, Miguel Angel Piris, Begoña Perez de Camino, Laura Pardo, Javier Cornago, Jose Luis Lopez-Lorenzo, Pilar Llamas, Laura Solan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Juan Carlos CaballeroHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0002-1798-9332
Elham AskariHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.
Nerea CarrascoInfectious Diseases Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.
Miguel Angel PirisPathology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0001-5839-3634
Begoña Perez de CaminoHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.
Laura PardoHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.
Javier CornagoHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0002-0737-4211
Jose Luis Lopez-LorenzoHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0003-1502-3902
Pilar LlamasHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.
Laura SolanHematology Department, Fundacion Jimenez Diaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0001-8949-8762
Hospital Universitario Fundación Jiménez Díaz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Waldenström macroglobulinemia (WM) is a slowly progressive hematologic malignancy that usually responds rapidly to treatment. Being a lymphoplasmacytoid neoplasm, it is associated with a monoclonal IgM component, which may be associated with multiple manifestations and symptoms. We report the case of a 77-year-old woman diagnosed with WM following the development of severe and sudden pancytopenia associated with a cold agglutinin syndrome. In order to treat the WM and the underlying hemolysis, treatment with rituximab, corticosteroids and cyclophosphamide was started. Despite the improvement in hemolysis parameters, pancytopenia persisted, and we started a second line with ibrutinib. During treatment the patient developed an uncommon invasive fungal infection (IFI) with bone marrow granulomatosis and myelofibrosis. This case shows an unusual clinical course with a poor hematopoietic response to treatment and a large number of intercurrent complications.

Indexed as

case reportgranulomatosisinvasive candidiasisWaldenström macroglobulinemia

Identifiers

PMID37189625
PMCPMC10135538
OpenAlexW4360849777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.