Evidence map›Paper›PMID 37189497›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Salivary ATR-FTIR Spectroscopy Coupled with Support Vector Machine Classification for Screening of Type 2 Diabetes Mellitus.

Douglas Carvalho Caixeta, Murillo Guimarães Carneiro, Ricardo Rodrigues, Deborah Cristina Teixeira Alves, Luís Ricardo Goulart, Thúlio Marquez Cunha, Foued Salmen Espindola, Rui Vitorino, Robinson Sabino-Silva

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Douglas Carvalho CaixetaInnovation Center in Salivary Diagnostic and Nanotheranostics, Department of Physiology, Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia 38408-100, Minas Gerais, Brazil.ORCID 0000-0002-2363-6584
Murillo Guimarães CarneiroFaculty of Computing, Federal University of Uberlandia, Uberlandia 38408-100, Minas Gerais, Brazil.ORCID 0000-0002-2915-8990
Ricardo RodriguesInnovation Center in Salivary Diagnostic and Nanotheranostics, Department of Physiology, Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia 38408-100, Minas Gerais, Brazil.
Deborah Cristina Teixeira AlvesInnovation Center in Salivary Diagnostic and Nanotheranostics, Department of Physiology, Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia 38408-100, Minas Gerais, Brazil.
Luís Ricardo GoulartInstitute of Biotechnology, Federal University of Uberlandia, Uberlandia 38408-100, Minas Gerais, Brazil.ORCID 0000-0002-1803-4861
Thúlio Marquez CunhaSchool of Medicine, Federal University of Uberlandia (UFU), Uberlandia 38408-100, Minas Gerais, Brazil.
Foued Salmen EspindolaInstitute of Biotechnology, Federal University of Uberlandia, Uberlandia 38408-100, Minas Gerais, Brazil.ORCID 0000-0002-6937-1411
Rui VitorinoInstitute of Biomedicine, Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-3636-5805
Robinson Sabino-SilvaInnovation Center in Salivary Diagnostic and Nanotheranostics, Department of Physiology, Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia 38408-100, Minas Gerais, Brazil.ORCID 0000-0002-2104-5780

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior #458143/2014Fundação de Amparo à Pesquisa do Estado de Minas Gerais #APQ-02872-16Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-03613-17National Council for Scientific and Technological Development N.: 403193/2022-2National Council for Scientific and Technological Development N.: 465669/2014-0
6 · The paper itself

Abstract

The blood diagnosis of diabetes mellitus (DM) is highly accurate; however, it is an invasive, high-cost, and painful procedure. In this context, the combination of ATR-FTIR spectroscopy and machine learning techniques in other biological samples has been used as an alternative tool to develop a non-invasive, fast, inexpensive, and label-free diagnostic or screening platform for several diseases, including DM. In this study, we used the ATR-FTIR tool associated with linear discriminant analysis (LDA) and a support vector machine (SVM) classifier in order to identify changes in salivary components to be used as alternative biomarkers for the diagnosis of type 2 DM. The band area values of 2962 cm

Indexed as

ATR-FTIRdiabetesdiagnosismachine learningsalivasalivary biomarkerssupport vector machine

Identifiers

PMID37189497
PMCPMC10137088

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.