ArticleDiagnostics (Basel, Switzerland)2023
Transperineal Prostate Biopsy Targeted by Magnetic Resonance Imaging Cognitive Fusion.
Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Advances in new ultrasound technologies in targeted prostate biopsy (Review).Experimental and therapeutic medicine · 2026Review
- Transperineal cognitive fusion MRI-targeted biopsy shows higher detection rates than systematic biopsy in prostate cancer: a prospective cohort study.BMC urology · 2025Article
- Comparative Analysis of Transperineal Cognitive Fusion, Systematic, and Combined Biopsies for Prostate Cancer Detection.Medicina (Kaunas, Lithuania) · 2025Article
- Research on application of multiparametric MRI to predict FNCLCC grading and ki67 expression in soft tissue sarcoma biopsy pathology: Based on a CT-MRI fusion image registration method.Frontiers in oncology · 2025Article
- Value of cognitive fusion targeted and standard systematic transrectal prostate biopsy for prostate cancer diagnosis.Asian journal of andrology · 2024Article
- Ultrasound-guided transperineal vs transrectal prostate biopsy: A meta-analysis of diagnostic accuracy and complication rates.Open medicine (Warsaw, Poland) · 2024Article
- Cognitive Fusion-Guided Transperineal Biopsy Leading to the Diagnosis of Early Prostate Adenocarcinoma After Repeated Negative Evaluations: A Case Report.Current health sciences journalArticle
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Prostate cancer is among the most frequently diagnosed cancers and a leading cause of cancer-related death in men. Currently, the most reliable and widely used imaging test for prostate cancer diagnosis is multiparametric pelvic magnetic resonance imaging (mpMRI). Modern biopsy techniques are based on the computerised merging of ultrasound and MRI images to provide better vision during the biopsy procedure (Fusion Biopsy). However, the method is expensive due to high equipment cost. Cognitive fusion of ultrasound and MRI images has recently emerged as a cheaper and easier alternative to computerised fusion. The aim of this prospective study is to perform an in-patient comparison of the systematic prostate biopsy procedure (SB) vs. cognitive fusion (CF) guided prostate biopsy method in terms of safety, ease of use, cancer detection rate and clinically significant cancer detection. We enrolled 103 patients with suspected prostate cancer that were biopsy naive, with PSA > 4 ng/dL and PIRADS score of 3, 4 or 5. All patients received a transperineal standard 12-18 cores systematic biopsy (SB) and a four-cores targeted cognitive fusion (CF) biopsy. Following the prostate biopsy, 68% of the patients were diagnosed with prostate cancer (70/103 patients). SB diagnosis rate was 62% while CF biopsy was slightly better with a 66% rate. There was a significant 20% increase in clinically significant prostate cancer detection rate for the CF compared to SB (
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