Evidence map›Paper›PMID 37189444›Full record

ArticleBiomolecules2023

Do Serum Galectin-9 Levels in Women with Gestational Diabetes and Healthy Ones Differ before or after Delivery? A Pilot Study.

Aleksandra Pełech, Monika Ruszała, Magdalena Niebrzydowska-Tatus, Katarzyna Bień, Żaneta Kimber-Trojnar, Monika Czuba, Małgorzata Świstowska, Bożena Leszczyńska-Gorzelak

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aleksandra PełechDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0002-7250-4326
Monika RuszałaDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Magdalena Niebrzydowska-TatusDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0002-9675-0919
Katarzyna BieńDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0001-6626-3063
Żaneta Kimber-TrojnarDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0001-7295-0409
Monika CzubaDepartment of Clinical Genetics, Medical University of Lublin, 20-080 Lublin, Poland.
Małgorzata ŚwistowskaDepartment of Clinical Genetics, Medical University of Lublin, 20-080 Lublin, Poland.ORCID 0000-0001-9366-3556
Bożena Leszczyńska-GorzelakDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is a common metabolic disease that occurs during pregnancy, with the placenta playing an important role in its pathophysiology. Currently, the role of galectin-9 in the development of GDM is unknown. The aim of this study was to compare galectin-9 concentrations in healthy pregnant women and those with GDM. Galectin-9 levels were assessed in serum samples taken both just before and after delivery, as well as in urine samples collected in the postpartum period. Maternal body composition and hydration status were evaluated using the bioelectrical impedance analysis (BIA) method. There were no statistically significant differences in the concentration of galectin-9 in women with GDM compared to healthy pregnant women in their serum samples taken just before delivery, nor in their serum and urine samples collected in the early postpartum period. However, serum galectin-9 concentrations taken before delivery were positively correlated with BMI and parameters related to the amount of adipose tissue assessed in the early postpartum period. Additionally, there was a correlation between serum galectin-9 concentrations taken before and after delivery. Galectin-9 is unlikely to become a diagnostic marker for GDM. However, this subject requires further clinical research in larger groups.

Indexed as

Diabetes, GestationalFemaleGalectinsHumansPilot ProjectsPlacentaPostpartum PeriodPregnancyGalectinsbioelectrical impedance analysisgalectin-9gestational diabetes mellituspregnancy

Identifiers

PMID37189444
PMCPMC10135713
OpenAlexW4366594181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.