Evidence map›Paper›PMID 37189421›Full record

ArticleBiomolecules2023

Combined In Vivo Microdialysis and PET Studies to Validate [

Anne Marlene Landau, Steen Jakobsen, Majken Borup Thomsen, Aage Kristian Olsen Alstrup, Dariusz Orlowski, Jan Jacobsen, Gregers Wegener, Arne Mørk, Jens Christian Hedemann Sørensen, Doris J Doudet

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Anne Marlene LandauTranslational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, A701, Palle Juul Jensens Boulevard 99, 8200 Aarhus, Denmark.ORCID 0000-0002-7371-8713
Steen JakobsenDepartment of Nuclear Medicine & PET-Center, Aarhus University Hospital, 8200 Aarhus, Denmark.
Majken Borup ThomsenTranslational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, A701, Palle Juul Jensens Boulevard 99, 8200 Aarhus, Denmark.
Aage Kristian Olsen AlstrupDepartment of Nuclear Medicine & PET-Center, Aarhus University Hospital, 8200 Aarhus, Denmark.ORCID 0000-0002-0084-9122
Dariusz OrlowskiCenter for Experimental Neuroscience (CENSE), Department of Neurosurgery, Aarhus University Hospital, 8200 Aarhus, Denmark.
Jan JacobsenDepartment of Nuclear Medicine & PET-Center, Aarhus University Hospital, 8200 Aarhus, Denmark.
Gregers WegenerTranslational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, A701, Palle Juul Jensens Boulevard 99, 8200 Aarhus, Denmark.ORCID 0000-0002-0081-0068
Arne MørkSynaptic Transmission, H. Lundbeck A/S, Ottiliavej 9, Valby, 2500 Copenhagen, Denmark.
Jens Christian Hedemann SørensenCenter for Experimental Neuroscience (CENSE), Department of Neurosurgery, Aarhus University Hospital, 8200 Aarhus, Denmark.
Doris J DoudetDepartment of Medicine/Neurology, University of British Columbia, 2221 Wesbrook Mall, Vancouver, BC V6T 2B5, Canada.
Aarhus University Hospital · DKAarhus University · DKLundbeck (Denmark) · DKUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The noradrenaline system attracts attention for its role in mood disorders and neurodegenerative diseases but the lack of well-validated methods impairs our understanding when assessing its function and release in vivo. This study combines simultaneous positron emission tomography (PET) and microdialysis to explore if [

Indexed as

NorepinephrinePositron Emission Tomography Computed TomographyAnimalsMicrodialysisPositron-Emission TomographyRenal DialysisSwine, MiniatureYohimbineNorepinephrineYohimbine[11C]yohimbinea2 adrenoceptorsmicrodialysisminipignoradrenalinepositron emission tomography

Identifiers

PMID37189421
PMCPMC10136072
OpenAlexW4365514052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.