Evidence map›Paper›PMID 37189126›Full record

ArticleCost effectiveness and resource allocation : C/E2023

The FLURESP European commission project: cost-effectiveness assessment of ten public health measures against influenza in Italy: is there an interest in COVID-19 pandemic?

Ariel Beresniak, Christian Napoli, John Oxford, Alejandra Daruich, Laurent Niddam, Gérard Duru, Alberto E Tozzi, Marta Ciofi Degli Atti, Danielle Dupont, Caterina Rizzo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Ariel BeresniakData Mining International, Geneva Business Terminal, Route de Pré-Bois, 14, 1216, Geneva, Switzerland. aberesniak@datamining-international.com.
Christian NapoliDepartment of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
John OxfordQueen Mary College, London, UK.
Alejandra DaruichUniversity Hospital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, AP-HP, Paris University, Paris, France.
Laurent NiddamNiddam European Community Lawyer, Budapest, Hungary.
Gérard DuruData Mining International, Geneva Business Terminal, Route de Pré-Bois, 14, 1216, Geneva, Switzerland.
Alberto E TozziIRCCS, Bambino Gesù Children's Hospital, Rome, Italy.
Marta Ciofi Degli AttiIRCCS, Bambino Gesù Children's Hospital, Rome, Italy.
Danielle DupontData Mining International, Geneva Business Terminal, Route de Pré-Bois, 14, 1216, Geneva, Switzerland.
Caterina Rizzo *IRCCS, Bambino Gesù Children's Hospital, Rome, Italy.
Dominique Bremond-Gignac *University Hospital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, AP-HP, Paris University, Paris, France.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAssistance Publique – Hôpitaux de Paris · FRBambino Gesù Children's Hospital · ITQueen Mary University of London · GBSapienza University of Rome · ITUniversité Paris Cité · FR

Funding

European Commission 2010-11-01
6 · The paper itself

Abstract

backgroundThe FLURESP project is a public health research funded by the European Commission, with the objective to design a methodological framework to assess the cost-effectiveness of existing public health measures against human influenza pandemics. A dataset has been specifically collected in the frame of the Italian health system. As most of interventions against human influenza are relavant against other respiratory diseases pandemics, potential interests in COVID-19 are discussed.

methodsTen public health measures against human influenza pandemics pandemic were selected to be also relevant to other respiratory virus pandemics such as COVID 19: individual (hand washing, using masks), border control (quarantine, fever screening, border closure), community infection (school closure, class dismissal, social distancing, limitation of public transport), reduction of secondary infections (implementation of antibiotic therapy guidelines), pneumococcal vaccination for at-risk people, development of Intensive Care Unit (ICU) capacity, implementation of life support equipments in ICU, screening interventions, vaccination programs targeting health professional and targeting general population.

resultsUsing mortality reduction as effectiveness criteria, the most cost-effective strategies are "reduction of secondary infections" and "implementation of life support equipment in ICU". The least cost-effective option whatever the level of pandemic events are screening interventions and mass vaccination.

conclusionsA number of intervention strategies against human influenza pandemics appears relevant against every respiratory virus, including the COVID-19 event. Measures against pandemics should be considered according to their expected effectiveness but also their costs for the society because they impose substantial burden to the population, confirming the interest of considering cost-effectiveness of public health measures to enlighten decision making.

Indexed as

Cost-EffectivenessCOVID-19Emergency preparednessHuman influenzaPandemicsSARS-CoV-2

Identifiers

PMID37189126
PMCPMC10184089
OpenAlexW4376610557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.