Evidence map›Paper›PMID 37188909›Full record

ArticleSurgical endoscopy2023

The severity and infection of acute pancreatitis may increase the risk of bleeding in patients undergoing EUS-guided drainage and endoscopic necrosectomy: a large retrospective cohort.

Siyang Peng, Qian Yao, Yunfeng Fu, Xuan Xu, SiHai Chen, Huajing Ke, Yang Hu, Huifang Xiong, Wenhua He, Yong Zhu and 8 more

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Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Siyang PengDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Qian YaoDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Yunfeng FuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Xuan XuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
SiHai ChenDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Huajing KeDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Yang HuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Huifang XiongDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Wenhua HeDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Yong ZhuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Liang XiaDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Yao WuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Xu ShuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhijian LiuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Yin ZhuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Youxiang ChenDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Nonghua LuDepartment of Gastroenterology, Pancreatic Disease Centre, First Affiliated Hospital of Nanchang University, Nanchang, China.
Pi LiuDepartment of Gastroenterology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, 518109, China. liupi126@sina.com.ORCID http://orcid.org/0000-0001-9693-7524
Nanchang University · CNSouthern Medical University Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been great progress in the use of endoscopic ultrasound (EUS)-guided drainage in acute pancreatitis patients using a novel lumen-apposing metal stent (LAMS) in the last decade, but some patients experience bleeding. Our research analyzed the preprocedural risk factors for bleeding.

methodsFrom July 13, 2016 to June 23, 2021, we retrospectively analyzed all patients who received endoscopic drainage by the LAMS in our hospital. Univariate and multivariate statistical analyses were used to identify the independent risk factors. We plotted ROC curves based on the independent risk factors.

resultsA total of 205 patients were analyzed and 5 patients were excluded. A total of 200 patients were included in our research. Thirty (15%) patients presented with bleeding. In the multivariate analysis, computed tomography severity index score (CTSI) score [odds ratio (OR), 2.66; 95% CI: 1.31-5.38; P = 0.007], positive blood cultures [odds ratio (OR), 5.35; 95% CI: 1.31-21.9; P = 0.02], and Acute Physiology and Chronic Health Evaluation II (APACHE II) score [odds ratio (OR), 1.14; 95% CI: 1. 01-1.29; P = 0.045] were associated with bleeding. The area under the ROC curve of the combined predictive indicator was 0.79.

conclusionBleeding in endoscopic drainage by the LAMS is significantly associated with the CTSI score, positive blood cultures, and APACHE II score. This result could help clinicians make more appropriate choices.

Indexed as

PancreatitisAcute DiseaseDrainageEndosonographyHemorrhageHumansRetrospective StudiesStentsTreatment OutcomeDebridementHemorrhageInfectious pancreatic necrosisLumen-apposing metal stentRisk factor

Identifiers

PMID37188909
OpenAlexW4376604355

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.