Evidence map›Paper›PMID 37188894›Full record

SynthesisObesity surgery2023

Effects of Sleeve Gastrectomy on Patients with Obesity and Polycystic Ovary Syndrome: a Meta-analysis.

Ping Luo, Zhihong Su, Pengzhou Li, Guohui Wang, Weizheng Li, Xulong Sun, Zhibing Fu, Hui Zhou, Xianhao Yi, Liyong Zhu and 1 more

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Ping LuoDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Zhihong SuDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Pengzhou LiDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Guohui WangDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Weizheng LiDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Xulong SunDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Zhibing FuDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Hui ZhouDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Xianhao YiDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Liyong ZhuDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China. zly8128@csu.edu.cn.
Shaihong ZhuDepartment of General Surgery, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China. shzhu@csu.edu.cn.ORCID 0000-0001-6209-3132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the efficacy of sleeve gastrectomy (SG) on patients with obesity and polycystic ovary syndrome (PCOS). MATERIALS AND

methodsWe searched PubMed, Embase, Cochrane Library, and Web of Science to identify relevant studies published prior to December 2, 2022. Meta-analysis was performed on menstrual irregularity, total testosterone, sex hormone-binding globulin (SHBG), anti-Mullerian hormone (AMH), glucolipid metabolism indicators, and body mass index (BMI) following SG.

resultsSix studies and 218 patients were included in the meta-analysis. Following SG, menstrual irregularity significantly decreased (odds ratio [OR] 0.03; 95% confidence intervals [CIs], 0.00-0.24; P=0.001). Additionally, SG can lower total testosterone levels (MD -0.73; 95% CIs -0.86-0.60; P< 0.0001), as well as BMI (MD -11.59; 95% CIs -13.10-10.08; P<0.0001). A significant increase was observed in the levels of SHBG and high-density lipoprotein (HDL) after SG. In addition to reducing fasting blood glucose, insulin, triglycerides (TG), and low-density lipoprotein levels, SG significantly reduced low-density lipoprotein levels as well.

conclusionsFollowing SG, we firstly demonstrated significant improvements in menstrual irregularity, testosterone and SHGB levels, glycolipid metabolism indicators, and BMI. Therefore, SG may be considered as a new option for the clinical treatment of patients with obesity and PCOS.

Indexed as

Obesity, MorbidPolycystic Ovary SyndromeFemaleGastrectomyHumansLipoproteins, LDLMenstruation DisturbancesObesityTestosteroneLipoproteins, LDLTestosteroneEfficacyObesityPolycystic ovary syndromeSleeve gastrectomy

Identifiers

PMID37188894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.