Evidence map›Paper›PMID 37188883›Full record

ArticleEuropean radiology2023

Deep learning HASTE sequence compared with T2-weighted BLADE sequence for liver MRI at 3 Tesla: a qualitative and quantitative prospective study.

Pierre Wary, Gabriela Hossu, Khalid Ambarki, Dominik Nickel, Simon Arberet, Julien Oster, Xavier Orry, Valérie Laurent

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04645628 (Optimization of the Acquisition Sequence to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04645628 narecruitingnot on this map

Optimization of the Acquisition Sequence to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam

TypeinterventionalSponsorCentral Hospital, Nancy, FranceRan2020 to 2028Enrolled720ConditionsHealthy Subjects, Patient Performing an MRI ExaminationArmsMRI examination
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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  14. Advanced MRI techniques in abdominal imaging.Abdominal radiology (New York) · 2024
    Review
  15. Article
  16. Deep Learning-accelerated MRI in Body and Chest.Journal of computer assisted tomography
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Pierre WaryDepartment of Adult Radiology, CHRU de Nancy, 5 Rue du Morvan, 54500, Vandoeuvre-lès-Nancy, France. P.WARY@chru-nancy.fr.ORCID http://orcid.org/0000-0002-6484-4136
Gabriela HossuClinical Investigation Center Technological Innovation of Nancy, Inserm, CHRU de Nancy, Vandoeuvre-lès-Nancy, France.
Khalid AmbarkiSiemens Healthcare, Siemens Healthcare SAS, Saint Denis, France.
Dominik NickelSiemens Healthcare GmbH, MR Application Predevelopment, Erlangen, Germany.
Simon ArberetSiemens Healthineers, Digital Technology & Innovation, Princeton, NJ, USA.
Julien OsterClinical Investigation Center Technological Innovation of Nancy, Inserm, CHRU de Nancy, Vandoeuvre-lès-Nancy, France.
Xavier OrryDepartment of Adult Radiology, CHRU de Nancy, 5 Rue du Morvan, 54500, Vandoeuvre-lès-Nancy, France.
Valérie LaurentDepartment of Adult Radiology, CHRU de Nancy, 5 Rue du Morvan, 54500, Vandoeuvre-lès-Nancy, France.
Inserm · FRCentre Hospitalier Régional et Universitaire de Nancy · FRSiemens (France) · FRSiemens Healthineers (Germany) · DESiemens (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo qualitatively and quantitatively compare a single breath-hold fast half-Fourier single-shot turbo spin echo sequence with deep learning reconstruction (DL HASTE) with T2-weighted BLADE sequence for liver MRI at 3 T.

methodsFrom December 2020 to January 2021, patients with liver MRI were prospectively included. For qualitative analysis, sequence quality, presence of artifacts, conspicuity, and presumed nature of the smallest lesion were assessed using the chi-squared and McNemar tests. For quantitative analysis, number of liver lesions, size of the smallest lesion, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) in both sequences were assessed using the paired Wilcoxon signed-rank test. Intraclass correlation coefficients (ICCs) and kappa coefficients were used to assess agreement between the two readers.

resultsOne hundred and twelve patients were evaluated. Overall image quality (p = .006), artifacts (p < .001), and conspicuity of the smallest lesion (p = .001) were significantly better for the DL HASTE sequence than for the T2-weighted BLADE sequence. Significantly more liver lesions were detected with the DL HASTE sequence (356 lesions) than with the T2-weighted BLADE sequence (320 lesions; p < .001). CNR was significantly higher for the DL HASTE sequence (p < .001). SNR was higher for the T2-weighted BLADE sequence (p < .001). Interreader agreement was moderate to excellent depending on the sequence. Of the 41 supernumerary lesions visible only on the DL HASTE sequence, 38 (93%) were true-positives.

conclusionThe DL HASTE sequence can be used to improve image quality and contrast and reduces artifacts, allowing the detection of more liver lesions than with the T2-weighted BLADE sequence. CLINICAL RELEVANCE STATEMENT: The DL HASTE sequence is superior to the T2-weighted BLADE sequence for the detection of focal liver lesions and can be used in daily practice as a standard sequence. KEY POINTS: • The half-Fourier acquisition single-shot turbo spin echo sequence with deep learning reconstruction (DL HASTE sequence) has better overall image quality, reduced artifacts (particularly motion artifacts), and improved contrast, allowing the detection of more liver lesions than with the T2-weighted BLADE sequence. • The acquisition time of the DL HASTE sequence is at least eight times faster (21 s) than that of the T2-weighted BLADE sequence (3-5 min). • The DL HASTE sequence could replace the conventional T2-weighted BLADE sequence to meet the growing indication for hepatic MRI in clinical practice, given its diagnostic and time-saving performance.

Indexed as

Deep LearningLiver NeoplasmsArtifactsHumansMagnetic Resonance ImagingProspective StudiesDeep learningDiagnostic imagingLiverMagnetic resonance imagingNeural networks, computer

Identifiers

PMID37188883
OpenAlexW4376601762

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.