Evidence map›Paper›PMID 37188880›Full record

ArticleCell research2023

Lin28a maintains a subset of adult muscle stem cells in an embryonic-like state.

Peng Wang, Xupeng Liu, Ziyue Yao, Yu Chen, Lanfang Luo, Kun Liang, Jun-Hao Elwin Tan, Min-Wen Jason Chua, Yan-Jiang Benjamin Chua, Shilin Ma and 16 more

Open access · greenAbstract read
In one paragraph

Article in Cell research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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  13. Architecture of intraflagellar transport complexes.Nature structural & molecular biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 4 institutions in 3 countries.

Peng Wang *Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Xupeng Liu *Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Ziyue YaoInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Yu ChenInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Lanfang LuoInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Kun LiangInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Jun-Hao Elwin TanNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
Min-Wen Jason ChuaNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
Yan-Jiang Benjamin ChuaNUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
Shilin MaInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Liping ZhangInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Wenwu MaInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Shuqing LiuInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Wenhua CaoInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Luyao GuoInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Lu GuangInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Yuefan WangInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
He ZhaoInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Na AiUniversity of Chinese Academy of Sciences, Beijing, China.
Yun LiUniversity of Chinese Academy of Sciences, Beijing, China.
Chunwei LiDepartment of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Ruiqi Rachel WangInstitute of Zoology, Chinese Academy of Sciences, Beijing, China.
Bin Tean TehLaboratory of Cancer Therapeutics, Program in Cancer and Stem Cell Biology, Duke-National University of Singapore Medical School, Singapore, Singapore.
Lan JiangCAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Kang YuDepartment of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Ng Shyh-ChangInstitute of Zoology, Chinese Academy of Sciences, Beijing, China. huangsq@ioz.ac.cn.ORCID 0000-0003-3138-9525
Chinese Academy of Sciences · CNAgency for Science, Technology and Research · SGChinese Academy of Medical Sciences & Peking Union Medical College · CNNational University of Singapore · SG

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

During homeostasis and after injury, adult muscle stem cells (MuSCs) activate to mediate muscle regeneration. However, much remains unclear regarding the heterogeneous capacity of MuSCs for self-renewal and regeneration. Here, we show that Lin28a is expressed in embryonic limb bud muscle progenitors, and that a rare reserve subset of Lin28a

Indexed as

Adult Stem CellsSatellite Cells, Skeletal MuscleAnimalsCell Self RenewalMiceMuscle Fibers, SkeletalMuscle, Skeletal

Identifiers

PMID37188880
PMCPMC10474071
OpenAlexW4376603475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.