Evidence map›Paper›PMID 37188780›Full record

ArticleVirchows Archiv : an international journal of pathology2023

Pelvic lymph node dissection for cervical or bladder cancer: embedding residual fat tissue offers no added value.

Jasmijn Vaneman, Heleen J van Beekhuizen, Joost L Boormans, Patricia C Ewing-Graham, Geert J L H van Leenders, Ramon G V Smolders, H Lena C van Doorn

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jasmijn VanemanDepartment of Gynecologic Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Molewaterplein 40, 3015GD, Rotterdam, The Netherlands.
Heleen J van BeekhuizenDepartment of Gynecologic Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Molewaterplein 40, 3015GD, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-8899-7412
Joost L BoormansDepartment of Urology, Erasmus MC Cancer Institute, University Medical Center, Molewaterplein 40, 3015GD, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-5127-0436
Patricia C Ewing-GrahamDepartment of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Molewaterplein 40, 3015GD, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-1779-1115
Geert J L H van LeendersDepartment of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Molewaterplein 40, 3015GD, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-2176-9102
Ramon G V SmoldersDepartment of Gynecologic Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Molewaterplein 40, 3015GD, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-5407-0878
H Lena C van DoornDepartment of Gynecologic Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Molewaterplein 40, 3015GD, Rotterdam, The Netherlands. H.vandoorn@erasmusmc.nl.ORCID http://orcid.org/0000-0003-1062-4485

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of lymph node metastases in pelvic lymph node dissection (PLND) is important for staging and treatment. Standard practice is to submit visible or palpable lymph nodes for histology. We assessed the added value of embedding all residual fatty tissue.Patients (n = 85) who underwent PLND for cervical (n = 50) or bladder cancer (n = 35) between 2017 and 2019 were included. Study approval was obtained (MEC-2022-0156, 18.03.2022, retrospectively registered).The median lymph node yield with conventional pathological dissection was 21 nodes (Interquartile range (IQR) 18-28). This led to discovery of positive lymph nodes in 17 (20%) patients. Extended pathological assessment found 7 (IQR 3-12) additional nodes, but did not result in identification of more node metastases.Histopathological analysis of residual fatty tissue harvested at PLND resulted in an increased lymph node yield, but not in the detection of additional lymph node metastases.

Indexed as

PelvisUrinary Bladder NeoplasmsHumansLymphatic MetastasisLymph Node ExcisionLymph NodesBladder cancerCervical cancerMetastatic lymph nodesPathologyPelvic node dissectionResidual fatty tissue

Identifiers

PMID37188780
PMCPMC10542728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.