Evidence map›Paper›PMID 37188773›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Characteristics and outcomes of neonatal opioid withdrawal syndrome in preterm infants: a retrospective cohort study in the current era.

Alicia Heyward, Nori Minich, Adriana C Hoffman, Anna Maria Hibbs, Lulu Zhao, Moira Crowley

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. A Review of Neonatal Selective Serotonin Reuptake Inhibitor Withdrawal Syndrome.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alicia HeywardDivision of Neonatology, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH, USA. Aheyward721@gmail.com.ORCID http://orcid.org/0000-0002-8831-1035
Nori MinichCase Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID http://orcid.org/0000-0001-5448-220X
Adriana C HoffmanCase Western Reserve University School of Medicine, Cleveland, OH, USA.
Anna Maria HibbsDivision of Neonatology, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH, USA.
Lulu ZhaoDepartment of Obstetrics and Gynecology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Moira CrowleyDivision of Neonatology, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-0381-0960
Rainbow Babies & Children's Hospital · USUniversity Hospitals of Cleveland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCompare Neonatal Opioid Withdrawal Syndrome (NOWS) in preterm and term infants. STUDY

designSingle center, retrospective chart review of all in-utero opioid exposed infants born between 2014 and 2019. Withdrawal symptoms were assessed using Modified Finnegan Assessment Tool.

resultsThirteen preterm (PT), 72 late preterm (LPT), and 178 term infants were included. Preterm and LPT compared to term infants had lower peak Finnegan scores (9/9 vs. 12) and received less pharmacologic treatment (23.1/44.4 vs. 66.3%). Similar onset, peak symptoms, and treatment duration was observed in LPT and term infants.

conclusionsPreterm and LPT infants have lower Finnegan scores and require less pharmacologic therapy for NOWS. It is unclear if this is because our current assessment tool does not capture their symptoms or if they truly have less withdrawal. Onset of NOWS is similar in LPT and term infant, thus LPT infants do not require prolonged hospital monitoring for NOWS.

Indexed as

Infant, PrematureNeonatal Abstinence SyndromeAnalgesics, OpioidHospitalsHumansInfantInfant, NewbornRetrospective StudiesAnalgesics, Opioid

Identifiers

PMID37188773
OpenAlexW4376612779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.