Evidence map›Paper›PMID 37188516›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

High-Fidelity Reproduction of Visual Signals by Electrical Stimulation in the Central Primate Retina.

Alex R Gogliettino, Sasidhar S Madugula, Lauren E Grosberg, Ramandeep S Vilkhu, Jeff Brown, Huy Nguyen, Alexandra Kling, Paweł Hottowy, Władysław Dąbrowski, Alexander Sher and 2 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Alex R GogliettinoNeurosciences PhD Program, Stanford University, Stanford, California 94305 alex.gogliettino@gmail.com.
Sasidhar S MadugulaNeurosciences PhD Program, Stanford University, Stanford, California 94305.
Lauren E GrosbergHansen Experimental Physics Laboratory, Stanford University, Stanford, California 94305.
Ramandeep S VilkhuHansen Experimental Physics Laboratory, Stanford University, Stanford, California 94305.
Jeff BrownHansen Experimental Physics Laboratory, Stanford University, Stanford, California 94305.ORCID 0000-0002-7845-1042
Huy NguyenHansen Experimental Physics Laboratory, Stanford University, Stanford, California 94305.
Alexandra KlingHansen Experimental Physics Laboratory, Stanford University, Stanford, California 94305.
Paweł HottowyFaculty of Physics and Applied Computer Science, AGH University of Science and Technology, 30-059, Kraków, Poland.
Władysław DąbrowskiFaculty of Physics and Applied Computer Science, AGH University of Science and Technology, 30-059, Kraków, Poland.ORCID 0000-0001-9061-9568
Alexander SherSanta Cruz Institute for Particle Physics, University of California, Santa Cruz, Santa Cruz, California 95064.
Alan M LitkeSanta Cruz Institute for Particle Physics, University of California, Santa Cruz, Santa Cruz, California 95064.ORCID 0000-0003-3973-3642
E J ChichilniskyHansen Experimental Physics Laboratory, Stanford University, Stanford, California 94305.ORCID 0000-0002-5613-0248
Stanford University · USAGH University of Krakow · PLUniversity of California, Santa Cruz · USNeurosciences Institute · US

Funding

Training Program in Basic NeuroscienceT32MH020016 · NIMH · STANFORD UNIVERSITY · PI Justin L Gardner, Merritt C Maduke · 1997 to 2026
$16.2M
Core Grant for Vision ResearchP30EY019005 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D · 2009 to 2018
$7.7M
Unique physiological properties of novel ganglion cell types in primate retinaR01EY029247 · NEI · STANFORD UNIVERSITY · PI EDUARDO CHICHILNISKY, Michael B Manookin · 2018 to 2026
$4.7M
Patterned Electrical Stimulation of the Retina for High-Resolution ProsthesesR01EY021271 · NEI · STANFORD UNIVERSITY · PI EDUARDO CHICHILNISKY · 2011 to 2026
$4.6M
Bi-directional neural interface for probing parallel visual pathwaysR01EY032900 · NEI · STANFORD UNIVERSITY · PI CHICHILNISKY, EDUARDO, COGAN, STUART F · 2021 to 2024
$2.8M
Relating spontaneous activity to electrical stimulation properties of primate retinal ganglion cellsF30EY030776 · NEI · STANFORD UNIVERSITY · PI MADUGULA, SASIDHAR · 2019 to 2022
$158k
Probing visual computations and electrical stimulation in the central macaque retina for high fidelity vision restorationF31EY033636 · NEI · STANFORD UNIVERSITY · PI GOGLIETTINO, ALEX RICHARD · 2022 to 2024
$97k
NEI NIH HHS F30 EY030776NEI NIH HHS F31 EY033636NEI NIH HHS P30 EY019005NEI NIH HHS R01 EY021271NEI NIH HHS R01 EY029247NEI NIH HHS R01 EY032900NIMH NIH HHS T32 MH020016
6 · The paper itself

Abstract

Electrical stimulation of retinal ganglion cells (RGCs) with electronic implants provides rudimentary artificial vision to people blinded by retinal degeneration. However, current devices stimulate indiscriminately and therefore cannot reproduce the intricate neural code of the retina. Recent work has demonstrated more precise activation of RGCs using focal electrical stimulation with multielectrode arrays in the peripheral macaque retina, but it is unclear how effective this can be in the central retina, which is required for high-resolution vision. This work probes the neural code and effectiveness of focal epiretinal stimulation in the central macaque retina, using large-scale electrical recording and stimulation

Indexed as

RetinaVisual ProsthesisAnimalsElectric StimulationMacacaPhotic StimulationProstheses and ImplantsRetinal Ganglion Cellselectrical stimulationepiretinalganglion cellimplantprimateprosthesisretina

Identifiers

PMID37188516
PMCPMC10286946
OpenAlexW4376604073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.