Evidence map›Paper›PMID 37188328›Full record

ArticleACS applied materials & interfaces2023

Fully Microfabricated Surface Acoustic Wave Tweezer for Collection of Submicron Particles and Human Blood Cells.

Armaghan Fakhfouri, Melanie Colditz, Citsabehsan Devendran, Kateryna Ivanova, Stefan Jacob, Adrian Neild, Andreas Winkler

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Armaghan FakhfouriLeibniz-IFW Dresden, Helmholtzstr. 20, 01069 Dresden, Germany.ORCID 0000-0001-8526-0095
Melanie ColditzLeibniz-IFW Dresden, Helmholtzstr. 20, 01069 Dresden, Germany.
Citsabehsan DevendranDepartment of Mechanical and Aerospace Engineering Monash University, Clayton, Victoria 3800, Australia.ORCID 0000-0002-7043-933X
Kateryna IvanovaLeibniz-IFW Dresden, Helmholtzstr. 20, 01069 Dresden, Germany.
Stefan JacobPhysikalisch-Technische Bundesanstalt, Bundesallee 100, 38116, Brunswick, Germany.
Adrian NeildDepartment of Mechanical and Aerospace Engineering Monash University, Clayton, Victoria 3800, Australia.ORCID 0000-0002-7571-2526
Andreas WinklerLeibniz-IFW Dresden, Helmholtzstr. 20, 01069 Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise manipulation of (sub)micron particles is key for the preparation, enrichment, and quality control in many biomedical applications. Surface acoustic waves (SAW) hold tremendous promise for manipulation of (bio)particles at the micron to nanoscale ranges. In commonly used SAW tweezers, particle manipulation relies on the direct acoustic radiation effect whose superior performance fades rapidly when progressing from micron to nanoscale particles due to the increasing dominance of a second order mechanism, termed acoustic streaming. Through reproducible and high-precision realization of stiff microchannels to reliably actuate the microchannel cross-section, here we introduce an approach that allows the otherwise competing acoustic streaming to complement the acoustic radiation effect. The synergetic effect of both mechanisms markedly enhances the manipulation of nanoparticles, down to 200 nm particles, even at relatively large wavelength (300 μm). Besides spherical particles ranging from 0.1 to 3 μm, we show collections of cells mixed with different sizes and shapes inherently existing in blood including erythrocytes, leukocytes, and thrombocytes.

Indexed as

NanoparticlesSoundAcousticsBlood CellsErythrocytesHumansacoustic tweezersacoustofluidicscell manipulationnanoparticle concentrationSurface acoustic waves

Identifiers

PMID37188328
PMCPMC10215297

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.