Evidence map›Paper›PMID 37188251›Full record

ArticleRSC advances2023

Novel quinoline/thiazinan-4-one hybrids; design, synthesis, and molecular docking studies as potential anti-bacterial candidates against MRSA.

Asmaa H Mohamed, Sara M Mostafa, Ashraf A Aly, Alaa A Hassan, Esraa M Osman, AbdElAziz A Nayl, Alan B Brown, Elshimaa M N Abdelhafez

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Asmaa H MohamedChemistry Department, Faculty of Science, Minia University El-Minia 61519 Egypt asmaa.hamouda@mu.edu.eg sara.ahmed@mu.edu.eg ashrafaly63@yahoo.com ashraf.shehata@mu.edu.eg alaahassan2001@mu.edu.eg esraamah33@gmail.com.
Sara M MostafaChemistry Department, Faculty of Science, Minia University El-Minia 61519 Egypt asmaa.hamouda@mu.edu.eg sara.ahmed@mu.edu.eg ashrafaly63@yahoo.com ashraf.shehata@mu.edu.eg alaahassan2001@mu.edu.eg esraamah33@gmail.com.ORCID https://orcid.org/0000-0001-6381-1300
Ashraf A AlyChemistry Department, Faculty of Science, Minia University El-Minia 61519 Egypt asmaa.hamouda@mu.edu.eg sara.ahmed@mu.edu.eg ashrafaly63@yahoo.com ashraf.shehata@mu.edu.eg alaahassan2001@mu.edu.eg esraamah33@gmail.com.ORCID https://orcid.org/0000-0002-0314-3408
Alaa A HassanChemistry Department, Faculty of Science, Minia University El-Minia 61519 Egypt asmaa.hamouda@mu.edu.eg sara.ahmed@mu.edu.eg ashrafaly63@yahoo.com ashraf.shehata@mu.edu.eg alaahassan2001@mu.edu.eg esraamah33@gmail.com.
Esraa M OsmanChemistry Department, Faculty of Science, Minia University El-Minia 61519 Egypt asmaa.hamouda@mu.edu.eg sara.ahmed@mu.edu.eg ashrafaly63@yahoo.com ashraf.shehata@mu.edu.eg alaahassan2001@mu.edu.eg esraamah33@gmail.com.
AbdElAziz A NaylDepartment of Chemistry, College of Science, Jouf University Sakaka 72341 Aljouf Saudi Arabia aanayel@ju.edu.sa.
Alan B BrownChemistry Department, Florida Institute of Technology Melbourne FL USA.ORCID https://orcid.org/0000-0002-2669-5598
Elshimaa M N AbdelhafezDepartment of Medicinal Chemistry, Faculty of Pharmacy, Minia University 61519 Minia Egypt.ORCID https://orcid.org/0000-0002-0078-5261
Minia University · EGFlorida Institute of Technology · USJouf University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an attempt to develop effective and safe antibacterial agents, we synthesized novel thiazinanones by combining the quinolone scaffold and the 1,3-thiazinan-4-one group by reaction between ((4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)methylene)hydrazinecarbothioamides and 2,3-diphenylcycloprop-2-enone in refluxing ethanol in the presence of triethyl amine as a catalyst. The structure of the synthesized compounds was characterized by spectral data and elemental analysis, IR, MS,

Identifiers

PMID37188251
PMCPMC10178015
OpenAlexW4376483792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.