Evidence map›Paper›PMID 37188221›Full record

ArticleBrain communications2023

Increased flexibility of brain dynamics in patients with multiple sclerosis.

Nina von Schwanenflug, Stefan P Koch, Stephan Krohn, Tommy A A Broeders, David M Lydon-Staley, Dani S Bassett, Menno M Schoonheim, Friedemann Paul, Carsten Finke

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Nina von SchwanenflugDepartment of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin 10098, Germany.ORCID https://orcid.org/0000-0001-5573-259X
Stefan P KochDepartment of Experimental Neurology, Center for Stroke Research Berlin, Berlin 10117, Germany.ORCID https://orcid.org/0000-0001-6606-6369
Stephan KrohnDepartment of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin 10098, Germany.ORCID https://orcid.org/0000-0003-0683-5386
Tommy A A BroedersDepartment of Anatomy and Neurosciences, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam 1007 MB, The Netherlands.ORCID https://orcid.org/0000-0003-2884-2827
David M Lydon-StaleyAnnenberg School for Communication, University of Pennsylvania, Philadelphia 19104, PA, USA.ORCID https://orcid.org/0000-0001-8702-3923
Dani S BassettDepartment of Biological Engineering, School of Engineering & Applied Science, University of Pennsylvania, Philadelphia 19104, PA, USA.ORCID https://orcid.org/0000-0002-6183-4493
Menno M SchoonheimDepartment of Anatomy and Neurosciences, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam 1007 MB, The Netherlands.ORCID https://orcid.org/0000-0002-2504-6959
Friedemann PaulDepartment of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin 10098, Germany.
Carsten FinkeDepartment of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin 10098, Germany.ORCID https://orcid.org/0000-0002-7665-1171
Humboldt-Universität zu Berlin · DEAmsterdam Neuroscience · NLCharité - Universitätsmedizin Berlin · DEMax Delbrück Center · DEUniversity of Pennsylvania · USUniversity of the Sciences · US

Funding

Person-specific dynamic networks of nicotine withdrawal: implications for smoking cessationK01DA047417 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI LYDON, DAVID MARTIN · 2019 to 2023
$763k
NIDA NIH HHS K01 DA047417
6 · The paper itself

Abstract

Patients with multiple sclerosis consistently show widespread changes in functional connectivity. Yet, alterations are heterogeneous across studies, underscoring the complexity of functional reorganization in multiple sclerosis. Here, we aim to provide new insights by applying a time-resolved graph-analytical framework to identify a clinically relevant pattern of dynamic functional connectivity reconfigurations in multiple sclerosis. Resting-state data from 75 patients with multiple sclerosis (

Indexed as

EDSSfunctional reorganizationtemporal core–peripherytime-varying functional connectivity

Identifiers

PMID37188221
PMCPMC10176242
OpenAlexW4367843443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.