Evidence map›Paper›PMID 37188163›Full record

ArticleNeuro-oncology practice2023

Lifestyle coaching is feasible in fatigued brain tumor patients: A phase I/feasibility, multi-center, mixed-methods randomized controlled trial.

Alasdair G Rooney, William Hewins, Amie Walker, Mairi Mackinnon, Lisa Withington, Sara Robson, Claire Torrens, Lisa E M Hopcroft, Antony Clark, Garry Anderson and 16 more

Abstract read
In one paragraph

Article in Neuro-oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Alasdair G RooneyCentre for Clinical Brain Sciences, University of Edinburgh, UK.
William HewinsCentre for Clinical Brain Sciences, University of Edinburgh, UK.
Amie WalkerCentre for Clinical Brain Sciences, University of Edinburgh, UK.
Mairi MackinnonNeuro-Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK.
Lisa WithingtonClinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Sara RobsonClinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Claire TorrensNursing, Midwifery, and Allied Health Professions Research Unit, University of Stirling, Stirling, UK.
Lisa E M HopcroftScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
Antony ClarkScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
Garry AndersonV3 Health, Linlithgow, UK.
Helen Bulbeckbrainstrust, the Brain Cancer People, UK.
Joanna DunlopScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
Michelle WelshScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
Aimee DysonClinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Julie EmersonClinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Carol Cochranebrainstrust, the Brain Cancer People, UK.
Robert HillScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
Jade CarruthersScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
Julia DayScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
David GillespieCentre for Clinical Brain Sciences, University of Edinburgh, UK.
Christopher HewittClinical Health Psychology, Astley-Ainslie Hospital, Edinburgh, UK.
Emanuela MolinariInstitute of Neurosciences, Queen Elizabeth University Hospital, Glasgow, UK.
Mary WellsScottish Clinical Trials Research Unit (SCTRU), Public Health Scotland, Edinburgh, UK.
Catherine McBainClinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Anthony J ChalmersNeuro-Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK.
Robin GrantCentre for Clinical Brain Sciences, University of Edinburgh, UK.

Funding

Medical Research Council MR/J000914/1MRF_ C0396
6 · The paper itself

Abstract

Background: There are no effective treatments for brain tumor-related fatigue. We studied the feasibility of two novel lifestyle coaching interventions in fatigued brain tumor patients. Methods: This phase I/feasibility multi-center RCT recruited patients with a clinically stable primary brain tumor and significant fatigue (mean Brief Fatigue Inventory [BFI] score ≥ 4/10). Participants were randomized in a 1-1-1 allocation ratio to: Control (usual care); Health Coaching ("HC", an eight-week program targeting lifestyle behaviors); or HC plus Activation Coaching ("HC + AC", further targeting self-efficacy). The primary outcome was feasibility of recruitment and retention. Secondary outcomes were intervention acceptability, which was evaluated via qualitative interview, and safety. Exploratory quantitative outcomes were measured at baseline (T0), post-interventions (T1, 10 weeks), and endpoint (T2, 16 weeks). Results: Conclusions: Lifestyle coaching interventions are feasible to deliver to fatigued brain tumor patients. They were manageable, acceptable, and safe, with preliminary evidence of benefit on fatigue and mental health outcomes. Larger trials of efficacy are justified.

Indexed as

brain tumorcoachingfatiguelifestyleRCT

Identifiers

PMID37188163
PMCPMC10180387

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.