ArticleAsian journal of transfusion science
Von Willebrand factor levels in healthy blood donors and their association with blood group: A tertiary care hospital-based study.
Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Blood Transfusion and ABO Blood Groups in Sickle Cell Disease.Medicina (Kaunas, Lithuania) · 2026Article
- Targeting von Willebrand factor selectively under inflammatory conditions.bioRxiv : the preprint server for biology · 2026Article
- Impact of ABO Blood Group on Bleeding and Clotting Time Among Healthy North Indian Males: A Pilot Study.Cureus · 2025Article
- Classic Coagulation Traits Vary According to Rh(D) (But Not ABO) Blood Groups.Hematology reports · 2025Article
- Irradiated red blood cell transfusion is associated with an increased incidence of deep vein thrombosis in trauma patients: a cohort study.BMC anesthesiology · 2025Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundvon Willebrand disease is a common inherited bleeding disorder caused by the deficiency of von Willebrand factor (vWF).
aimsThe aim of this study was to evaluate plasma vWF levels and fVIII levels in healthy donors and its association with the ABO blood group.
methodsThis study was done in 2016 healthy adult blood donors. Complete history and relevant examination were done along with ABO and Rh (D) blood group typing, complete blood count, prothrombin time, activated partial thromboplastin time, vWF antigen (Ag) level, fVIII coagulant assay, and other tests for hemostasis. STATISTICAL ANALYSIS USED: Data were expressed in proportions and mean, median, and standard deviation, respectively. An appropriate test of significance was applied. RESULTS AND
conclusionsvWF level of donors ranged from 24 to 186 IU/dL with a mean of 96.31 IU/dL. Low vWF Ag level (below 50 IU/dl) was found in 2.5% of donors while 0.1% (2/2016) had level <30 IU/dL. O Rh (D)-positive blood group donors had the lowest vWF level (87.85 IU/dL), while ARh (D)-negative donors had the highest vWF level (117.27 IU/dL). fVIII level of the donor population ranged from 22% to 174%, with a mean of 98.82%. About 2.48% of donors had fVIII levels below 50%. There was a statistically significant correlation between fVIII level and vWF level (
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