Evidence map›Paper›PMID 37187264›Full record

ArticleMagnetic resonance imaging2023

Arterial spin labeled perfusion imaging with balanced steady-state free precession readout and radial sampling.

Paul Kyu Han, Thibault Marin, Yue Zhuo, Jinsong Ouyang, Georges El Fakhri, Chao Ma

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Paul Kyu HanGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, United States; Department of Radiology, Harvard Medical School, Boston, MA, United States.
Thibault MarinGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, United States; Department of Radiology, Harvard Medical School, Boston, MA, United States.
Yue ZhuoGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, United States; Department of Radiology, Harvard Medical School, Boston, MA, United States.
Jinsong OuyangGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, United States; Department of Radiology, Harvard Medical School, Boston, MA, United States.
Georges El FakhriGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, United States; Department of Radiology, Harvard Medical School, Boston, MA, United States.
Chao MaGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, United States; Department of Radiology, Harvard Medical School, Boston, MA, United States. Electronic address: cma5@mgh.harvard.edu.
Harvard University · US

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
Quantitative Oncologic PET-MRR01CA165221 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2012 to 2023
$4.7M
Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
PET/MR Mapping of Myocardial Membrane PotentialR01HL137230 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2017 to 2020
$3.3M
Improving Image-Guided Radiation Therapy of Gliomas with High-Resolution MR Spectroscopic ImagingR01EB033582 · NIBIB · YALE UNIVERSITY · PI Chao Ma · 2022 to 2026
$2.0M
Permeability Imaging using Simultaneous Dynamic PET and Arterial Spin Labeling MRIK01EB030045 · NIBIB · YALE UNIVERSITY · PI HAN, PAUL KYU · 2020 to 2023
$497k
NCI NIH HHS R01 CA165221NHLBI NIH HHS R01 HL137230NIBIB NIH HHS K01 EB030045NIBIB NIH HHS P41 EB022544NIBIB NIH HHS R01 EB033582NIBIB NIH HHS T32 EB013180
6 · The paper itself

Abstract

purposeTo develop an arterial spin labeling (ASL) perfusion imaging method with balanced steady-state free precession (bSSFP) readout and radial sampling for improved SNR and robustness to motion and off-resonance effects.

methodsAn ASL perfusion imaging method was developed with pseudo-continuous arterial spin labeling (pCASL) and bSSFP readout. Three-dimensional (3D) k-space data were collected in segmented acquisitions following a stack-of-stars sampling trajectory. Multiple phase-cycling technique was utilized to improve the robustness to off-resonance effects. Parallel imaging with sparsity-constrained image reconstruction was used to accelerate imaging or increase the spatial coverage.

resultsASL with bSSFP readout showed higher spatial and temporal SNRs of the gray matter perfusion signal compared to those from spoiled gradient-recalled acquisition (SPGR). Cartesian and radial sampling schemes showed similar spatial and temporal SNRs, regardless of the imaging readout. In case of severe B

conclusionsThe developed method allows non-invasive perfusion imaging of the whole-brain with relatively high SNR and robustness to motion and off-resonance effects in a practically feasible imaging time.

Indexed as

ArteriesImage Processing, Computer-AssistedBrainImaging, Three-DimensionalMagnetic Resonance ImagingPerfusionPerfusion ImagingSpin LabelsSpin Labels3 TArterial spin labelingBalanced steady-state free precessionPerfusionPhase-cyclingRadial

Identifiers

PMID37187264
PMCPMC10524790
OpenAlexW4376619513

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.