Evidence map›Paper›PMID 37186837›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Architecture and genomic arrangement of the MurE-MurF bacterial cell wall biosynthesis complex.

Karina T Shirakawa, Fernanda Angélica Sala, Mayara M Miyachiro, Viviana Job, Daniel Maragno Trindade, Andréa Dessen

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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  10. ExploringFrontiers in pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Karina T ShirakawaBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo 13084-971, Brazil.ORCID 0000-0003-2057-7520
Fernanda Angélica SalaBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo 13084-971, Brazil.
Mayara M MiyachiroUniv. Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, Bacterial Pathogenesis Group, Grenoble F-38044, France.
Viviana JobUniv. Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, Bacterial Pathogenesis Group, Grenoble F-38044, France.ORCID 0000-0001-8421-5292
Daniel Maragno TrindadeBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo 13084-971, Brazil.ORCID 0000-0002-8005-8784
Andréa DessenBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, São Paulo 13084-971, Brazil.ORCID 0000-0001-6487-4020
Centre National de la Recherche Scientifique · FRBrazilian Center for Research in Energy and Materials · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptidoglycan (PG) is a central component of the bacterial cell wall, and the disruption of its biosynthetic pathway has been a successful antibacterial strategy for decades. PG biosynthesis is initiated in the cytoplasm through sequential reactions catalyzed by Mur enzymes that have been suggested to associate into a multimembered complex. This idea is supported by the observation that in many eubacteria,

Indexed as

BacteriaBacterial ProteinsCell WallGenomicsLigasesPeptide SynthasesPeptidoglycanBacterial ProteinsLigasesPeptide SynthasesPeptidoglycanBordetella sppchimeric proteinsMur ligasespeptidoglycan

Identifiers

PMID37186837
PMCPMC10214165
OpenAlexW4376602758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.