Evidence map›Paper›PMID 37186823›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Cell-type memory in a single-cell eukaryote requires the continuous presence of a specific transcription regulator.

Chien-Der Lee, Naomi Ziv, Alexander D Johnson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chien-Der LeeDepartment of Microbiology and Immunology, University of California, San Francisco, CA 94158.ORCID 0000-0002-6093-9613
Naomi ZivDepartment of Microbiology and Immunology, University of California, San Francisco, CA 94158.
Alexander D JohnsonDepartment of Microbiology and Immunology, University of California, San Francisco, CA 94158.ORCID 0000-0003-4503-3327

Funding

Regulatory Circuits and Virulence in Candida albicansR01AI049187 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, ALEXANDER D · 2001 to 2021
$13.1M
MECHANISMS OF YEAST TRANSCRIPTIONAL REGULATORSR01GM037049 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, ALEXANDER D · 1986 to 2024
$9.4M
Illumina NovaSeq 6000 Sequencing SystemS10OD028511 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOW, ERIC D · 2020 to 2020
$583k
NIAID NIH HHS R01 AI049187NIGMS NIH HHS R01 GM037049NIH HHS S10 OD028511
6 · The paper itself

Abstract

A fundamental question in biology is how a eukaryotic cell type can be stably maintained through many rounds of DNA replication and cell division. In this paper, we investigate this question in a fungal species,

Indexed as

EukaryotaEukaryotic CellsCandida albicansCell CycleFungal ProteinsGene Expression Regulation, FungalPhenotypeTranscription FactorsFungal ProteinsTranscription FactorsCandida albicanscell-type memorydegrontranscriptional feedback loop

Identifiers

PMID37186823
PMCPMC10214202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.