Evidence map›Paper›PMID 37186815›Full record

ArticleDiabetes & vascular disease research

Comparative study of microvascular structural changes in the gestational diabetic placenta.

Xinyan Liang, Jiaqi Zhang, Yu Wang, You Wu, Hui Liu, Wei Feng, Ziyi Si, Ruige Sun, Zizhou Hao, Hongzhi Guo and 6 more

Abstract read
In one paragraph

Article in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Gestational diabetes mellitus and vascular malperfusion lesions in the placenta: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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  18. α-Glucosidase inhibitory potential ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xinyan LiangPostgraduate Training Base of Xiangyang First People's Hospital, Jinzhou Medical University, Xiangyang, China.
Jiaqi ZhangDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Yu WangDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.ORCID 0000-0001-6282-9840
You WuDepartment of Medical Imaging, Changsha Medical College, Changsha, China.
Hui LiuDepartment of Medical Imaging, Changsha Medical College, Changsha, China.
Wei FengDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Ziyi SiDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Ruige SunDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Zizhou HaoDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Hongzhi GuoPostgraduate Training Base of Xiangyang First People's Hospital, Jinzhou Medical University, Xiangyang, China.
Xue LiDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Tao XuDepartment of Ultrasound, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Mofeng WangPostgraduate Training Base of Xiangyang First People's Hospital, Jinzhou Medical University, Xiangyang, China.
Zhen NanPostgraduate Training Base of Xiangyang First People's Hospital, Jinzhou Medical University, Xiangyang, China.
Yang LvXiangyang Maternal and Child Health Hospital, Xiangyang, China.
Xinan ShangXiangzhou District People's Hospital, Xiangyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMicrovascular morphology and pathological changes in gestational diabetes mellitus (GDM) placentas and normal placentas were observed via vascular casting technology, electron microscopy, and pathological detection technology. Vascular structure and histological morphology changes in GDM placentas were examined to generate basic experimental data for the diagnosis and prognostic determination of GDM.

methodsThis case-control study involving 60 placentas, 30 from healthy controls and 30 from patients with GDM. Differences in size, weight, volume, umbilical cord diameter, and gestational age were assessed. Histological changes in the placentas in the two groups were analyzed and compared. A placental vessel casting model was constructed using a self-setting dental powder technique, to compare the two groups. The placental cast microvessels of the two groups were compared using scanning electron microscopy.

resultsThere were no significant differences in maternal age or gestational age between the GDM group and the control group (

conclusionGestational diabetes can cause gross and histological changes in the placenta, particularly placental microvascular changes.

Indexed as

Diabetes, GestationalPlacentaCase-Control StudiesFemaleGestational AgeHumansPregnancyBlood vessel castinggestational diabetesgross morphologymicrovasculaturepathological changesplacenta

Identifiers

PMID37186815
PMCPMC10192807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.